383169-64-0Relevant articles and documents
Design, synthesis and biological evaluation of novel thiazole derivatives as potent FabH inhibitors
Lv, Peng-Cheng,Wang, Kai-Rui,Yang, Ying,Mao, Wen-Jun,Chen, Jin,Xiong, Jing,Zhu, Hai-Liang
, p. 6750 - 6754 (2009)
Fatty acid biosynthesis is essential for bacterial survival. Components of this biosynthetic pathway have been identified as attractive targets for the development of new antibacterial agents. FabH, β-ketoacyl-acyl carrier protein (ACP) synthase III, is a