36449-43-1

Basic information

• Product Name: Hydrazinecarbothioamide, 2-[(4-bromophenyl)methylene]-
• Synonyms: 2-(4-bromobenzylidene)hydrazinecarbothioamide;Hydrazinecarbothioamide,2-[(4-bromophenyl)methylene];4-bromobenzaldehyde thiosemicarbazone
• CAS NO: 36449-43-1
• Molecular Formula: C8H8BrN3S
• Molecular Weight: 258.142
• Mol File: 36449-43-1.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Hydrazinecarbothioamide, 2-[(4-bromophenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarbothioamide, 2-[(4-bromophenyl)methylene]-(36449-43-1)
• EPA Substance Registry System: Hydrazinecarbothioamide, 2-[(4-bromophenyl)methylene]-(36449-43-1)

Safety Data

• Hazardous Substances Data: 36449-43-1(Hazardous Substances Data)

Usage

Uses

2-[(4-Bromophenyl)methylene]hydrazinecarbothioamide, is an amino acid derivative that can be used as a potential antitubercular (combats tuberculosis bacteria) drug.

Upstream product

• 79-19-6 thiosemicarbazide 
• 1122-91-4 4-bromo-benzaldehyde 
• 1247148-65-7 C₉H₂₀N₈S₃ 

Downstream Products

• 1172616-85-1 bis-[3-(2-(4-bromophenylmethyliden)hydrazo-1,3-thiazol-4-yl)-4-hydroxy-2H-chromen-2-one-6-yl]methane 
• 321980-83-0 2-(2-(4-bromobenzylidene)hydrazinyl)thiazol-4(5H)-one 
• 383169-64-0 C₁₆H₁₀BrCl₂N₃S 
• 351444-20-7 2-(2-(4-bromobenzylidene)hydrazinyl)-4-(4-chlorophenyl)thiazole 
• 307325-15-1 2-(2-(4-bromobenzylidene)hydrazinyl)-4-phenylthiazole 
• 337501-59-4 N-(4-acetyl-5-(4-bromophenyl)-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide 
• 321945-34-0 C₁₉H₁₂BrN₃O₂S 
• 307325-15-1 2-[(4-bromobenzylidene)hydrazono]-4-phenyl-2,3-dihydrothiazole 
• 1416961-52-8 4-acetyl-5-(1,2,3,4,5-penta-O-acetyl-D-mannopentitolyl)-2-{2-[(4-bromobenzylidene)hydrazono]-4-phenyl-2,3-dihydrothiazol-3-ylmethyl}-1,3,4-oxadiazoline 
• 1416961-53-9 4-acetyl-5-(1,2,3,4,5-penta-O-acetyl-D-galactopentitolyl)-2-{2-[(4-bromobenzylidene)hydrazono]-4-phenyl-2,3-dihydrothiazol-3-ylmethyl}-1,3,4-oxadiazoline 
• 1416961-42-6 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-[(4-bromobenzylidene)hydrazono]-4-phenyl-2,3-dihydrothiazole 
• 1416961-43-7 3-(β-D-glucopyranosyl)-2-[(4-bromobenzylidene)hydrazono]-4-phenyl-2,3-dihydrothiazole 
• 1416961-45-9 C₁₈H₁₆BrN₅OS 
• 1427160-34-6 N-[4-(1H-benzoimidazol-2-yl)thiazol-2-yl]-N'-(4-bromobenzylidene)hydrazine 

Relevant articles and documents

Synthesis of isothiosemicarbazones of potential antitumoral activity through a multicomponent reaction involving allylic bromides, carbonyl compounds and thiosemicarbazide

A convenient route for the synthesis of isothiosemicarbazones and 2-hydrazono-1,3-thiazin-4-ones through a multicomponent reaction featuring allylic bromides, carbonyl compounds and thiosemicarbazides is described. The transformations proceed under mild a

Assessment of Thiosemicarbazone-Containing Compounds as Potential Antileukemia Agents against P-gp Overexpressing Drug Resistant K562/A02 Cells

P-Glycoprotein (P-gp) overexpression is considered to be the leading cause of multidrug resistance (MDR) and failure of chemotherapy for leukemia. In this study, seventeen thiosemicarbazone-containing compounds were prepared and evaluated as potential ant

Synthesis of Emodin Amide Derivatives Containing 1,3,4-Thiadiazole and Their Inhibitory Activity on Vibrio harveyi

A series of new 1,3,4-thiadiazole Emodin amide derivatives were synthesized through the connection of 5-substituted-1,3,4-thiadiazole-2-amine and Emodin carboxylic acids which were obtained by a two-step procedure starting from Emodin. Vibrio harveyi inhibition activities of the newly prepared compounds were evaluated. Results revealed that all compounds showed different degrees of inhibition on V. harveyi. Among them, compound 7a showed the best V. harveyi inhibition effect and the minimum inhibitory concentration (MIC) was 0.0625 mg/mL.