383176-01-0

Basic information

• Product Name: Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethoxyphenyl]-
• CAS NO: 383176-01-0
• Molecular Formula: C16H26O4Si
• Molecular Weight: 310.466
• Mol File: 383176-01-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethoxyphenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethoxyphenyl]-(383176-01-0)
• EPA Substance Registry System: Ethanone, 1-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethoxyphenyl]-(383176-01-0)

Safety Data

• Hazardous Substances Data: 383176-01-0(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 2478-38-8 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 134-96-3 syringic aldehyde 
• 106852-80-6 4-(t-butyldimethylsilyloxy)-3,5-dimethoxybenzaldehyde 
• 926907-29-1 1-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-ethanol 

Downstream Products

• 2478-38-8 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone 
• 690666-07-0 3-[5-(benzo[b]thien-2-yl)-2,4-dimethoxyphenyl]-1-(4-hydroxy-3,5-dimethoxyphenyl)-2-propen-1-one 
• 926907-24-6 methanesulfonic acid 2,6-dimethoxy-4-[5-methoxy-7-(2-methyl-[1,3]dioxolan-2-yl)-3-methylene-2,3-dihydro-benzo[1,4]dioxin-2-yl]-phenyl ester 

Relevant articles and documents

Inverse electron demand hetero-Diels-Alder reaction in preparing 1,4-benzodioxin from o-quinone and enamine

A process for synthesizing 1,4-benzodioxin, through oxidation of a phenol to an o-quinone followed by treatment with an enamine, has been developed. Adduct stereochemistry is found to be retained via this one-pot reaction. The method uses hypervalent iodine reagent under mild conditions and is compatible with a wide scope of phenols and enamines.

1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders

It has been discovered certain 1,3-bis-(substituted-phenyl)-2-propen-1-ones, including compounds of formula (I) inhibit the expression of VCAM-1, and thus can be used to treat a patient with a disorder mediated by VCAM-1. Examples of inflammatory disorder