383191-80-8

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 352422-92-5 (1R,3R,4R,5R,8R)-5,8-Bis(benzyloxy)-4-hydroxy-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]oct-6-ene 

Downstream Products

• 383191-81-9 (1R,3R,4S,5R,8R)-5,8-Bis(benzyloxy)-4-hydroxy-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]oct-6-ene 
• 383191-88-6 (1S,3S,4R,6R,7R,8R,9R)-8-Benzoyloxy-9-(4,4'-dimethoxytrityloxy)-7-hydroxy-4-(thymin-1-yl)-2,5-dioxatricyclo[4.2.1.0^3,7]nonane 
• 383191-86-4 (1S,3S,4R,6R,7R,8R,9R)-8-Benzoyloxy-7,9-bis(benzyloxy)-4-(3-N-benzyloxymethylthymin-1-yl)-2,5-dioxatricyclo[4.2.1.0^3,7]nonane 
• 383191-83-1 (1R,3R,4S,5R,6R,7R,8R)-5,8-Bis(benzyloxy)-4,6-dihydroxy-3-(thymin-1-yl)-7-(4-tolylsulfonyloxy)-2-oxabicyclo[3.3.0]octane 
• 383191-84-2 (1S,3S,4R,6R,7R,8R,9R)-7,9-Bis(benzyloxy)-8-hydroxy-4-(3-N-benzyloxymethylthymin-1-yl)-2,5-dioxatricyclo[4.2.1.0^3,7]nonane 
• 383191-82-0 (1R,3R,4S,5R,6R,7R,8R)-5,8-Bis(benzyloxy)-4,6,7-trihydroxy-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]octane 
• 383191-87-5 (1S,3S,4R,6R,7R,8R,9R)-8-Benzoyloxy-7,9-dihydroxy-4-(thymin-1-yl)-2,5-dioxatricyclo[4.2.1.0^3,7]nonane 

Relevant academic research and scientific papers

A conformationally locked tricyclic nucleoside. Synthesis, crystal structure and incorporation into oligonucleotides

A tricyclic nucleoside is synthesised from a bicyclic nucleoside precursor by applying a stereoselective dihydroxylation, a regioselective tosylation and an intramolecular ether formation. This tricyclic nucleoside is constructed as a conformationally loc