38333-35-6

Usage

Uses

Used in Organic Synthesis:
(h4-Benzylideneacetone)tricarbonyliron is used as a catalyst in organic synthesis, particularly for the formation of carbon-carbon bonds. The presence of the benzylideneacetone ligand provides the compound with enhanced reactivity and selectivity, making it suitable for a wide range of chemical transformations.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (h4-Benzylideneacetone)tricarbonyliron is used as a catalyst for the synthesis of complex organic molecules with high efficiency and selectivity. This is crucial for the development of new drugs and the improvement of existing ones, as it allows for the creation of more effective and targeted treatments.
Used in Chemical Research:
(h4-Benzylideneacetone)tricarbonyliron is also utilized in chemical research as a catalyst for various reactions, enabling scientists to study and understand the underlying mechanisms of these transformations. This knowledge can then be applied to develop new synthetic methods and improve existing ones, ultimately contributing to the advancement of the field of chemistry.
Overall, (h4-Benzylideneacetone)tricarbonyliron is a versatile and important reagent in the fields of organic chemistry, pharmaceutical industry, and chemical research, playing a crucial role in the development of new synthetic methods and the creation of complex organic molecules with high efficiency and selectivity.

Upstream product

• 13463-40-6 iron pentacarbonyl 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 15321-51-4 diiron nonacarbonyl 
• 56665-21-5 fc-C=CHCo₂(CO)8 

Downstream Products

• 56556-41-3 Fe(CO)2(C₆H₅CHCHCOCH₃)P(C₆H₅)3 
• 21255-52-7 trans-Fe(CO)₃(triphenylphosphine)₂ 
• 83846-09-7 N₃P₃(OC₆H₄P(C₆H₅)2)2Fe(CO)3(OC₆H₄P(C₆H₅)2)4 
• 83846-06-4 Fe(CO)3((P(C₆H₅)2C₆H₄O)P₃N₃(OC₆H₅)5)2 
• 40757-44-6 trans-Fe(CO)3(PPh₂Me)2 
• 12152-72-6 (cyclohexa-1,3-diene)iron tricarbonyl 
• 25234-75-7 4-phenyl-2,5-nonanedione 
• 821775-44-4 tricarbonyl(3-methyl-5-phenyl-1-oxapenta-1,2,4-triene)iron⁽⁰⁾ 
• 25234-74-6 3-phenylhexane-2,5-dione 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 25234-76-8 1,2-diphenyl-1,4-pentanedione 
• 123543-16-8 C₆H₅(CH)2C(CH₃)COFe(CO)2P(C₆H₅)3 
• 38720-23-9 (η4-chalcone)Fe(CO)3 
• 93984-14-6 (benzylideneacetone)dicarbonyl(triphenyl phosphite)iron⁽⁰⁾ 

Relevant academic research and scientific papers

Thermal decomposition and stability of [Fe(η4-enone)(CO) 2L] complexes (L=CO and PPh3)

The compounds [Fe(bda)(CO)2L] and [Fe(ch)(CO)2L], (bda=benzylideneacetone; ch=chalcone; L=CO, PPh3) were investigated by thermogravimetry and derivative thermogravimetry (TG and DTG). The fragmentation patterns suggest that the iron

Iron Catalyzed Hydroformylation of Alkenes under Mild Conditions: Evidence of an Fe(II) Catalyzed Process

Earth abundant, first row transition metals offer a cheap and sustainable alternative to the rare and precious metals. However, utilization of first row metals in catalysis requires harsh reaction conditions, suffers from limited activity, and fails to tolerate functional groups. Reported here is a highly efficient iron catalyzed hydroformylation of alkenes under mild conditions. This protocol operates at 10-30 bar syngas pressure below 100 °C, utilizes readily available ligands, and applies to an array of olefins. Thus, the iron precursor [HFe(CO)4]-[Ph3PNPPh3]+ (1) in the presence of triphenyl phosphine catalyzes the hydroformylation of 1-hexene (S2), 1-octene (S1), 1-decene (S3), 1-dodecene (S4), 1-octadecene (S5), trimethoxy(vinyl)silane (S6), trimethyl(vinyl)silane (S7), cardanol (S8), 2,3-dihydrofuran (S9), allyl malonic acid (S10), styrene (S11), 4-methylstyrene (S12), 4-iBu-styrene (S13), 4-tBu-styrene (S14), 4-methoxy styrene (S15), 4-acetoxy styrene (S16), 4-bromo styrene (S17), 4-chloro styrene (S18), 4-vinylbenzonitrile (S19), 4-vinylbenzoic acid (S20), and allyl benzene (S21) to corresponding aldehydes in good to excellent yields. Both electron donating and electron withdrawing substituents could be tolerated and excellent conversions were obtained for S11-S20. Remarkably, the addition of 1 mol % acetic acid promotes the reaction to completion within 16-24 h. Detailed mechanistic investigations revealed in situ formation of an iron-dihydride complex [H2Fe(CO)2(PPh3)2] (A) as an active catalytic species. This finding was further supported by cyclic voltammetry investigations and intermediacy of an Fe(0)-Fe(II) species was established. Combined experimental and computational investigations support the existence of an iron-dihydride as the catalyst resting state, which then follows a Fe(II) based catalytic cycle to produce aldehyde.

Synthesis and expansion reaction of ferrocenylacetylene dimetal carbonyl compounds. The molecular structures of μ-FcCCHCoMo(CO)5Cp and μ3-FcCHCFeCo2(CO)9

Two ferrocenylacetylene dimetal carbonyl clusters μ-FcCCHCo(CO)3M(CO)2Cp (2, M=Mo; 3, M=W) were obtained from the reactions of the precursor μ-FcCCHCo2(CO)6 1 with metal exchange reagents NaM(CO)3Cp in THF under reflux. The dimetal compounds 1, 2, and 3 can further react with Fe2(CO)9 in the presence of benzylideneacetone (BDA) to give the corresponding μ3-ferrocenylvinylidene bridged trimetal clusters μ3-FcCHCFeCo2(CO)9 4 and μ3-FcCHCFeCoM(CO)8Cp (5, M=Mo; 6, M=W), respectively, probably through the formation of the intermediate (BDA)Fe(CO)3 which acts as an Fe(CO)3 transfer-reagent. The new compounds 2-6 were characterized by C/H analysis, IR and 1H-NMR spectrocopies. The molecular structures of 2 and 4 were determined by X-ray structural analysis. 2 is triclinic with space group P1 (#2), a=8.733(2) A, b=14.870(3) A, c=8.200(2) A, α=92.77(2)°, β=101.78(2)°, γ=78.41(2)°, V=1021.2(4) A3, and Z=2; final R=0.025, Rw=0.034 for 2988 reflections. Cluster 4 is orthorhombic with space group P212121 (#19), a=12.186(5) A, b=14.870(5) A, c=7.800(6) A, V=2340(2) A3 and Z=4; final R=0.062, Rw=0.065 for 2401 reflections.

Resolution of 4-benzylideneacetone)Fe(CO)3>. Structure and configurational stability of *> (L* = (+)-neomenthyldiphenylphosphine

Resolution of 4-benzylideneacetone)Fe(CO)3> has been achieved by (reversible) thermal displacement of a CO ligand by use of the chiral phosphine (+)-neomenthyldiphenylphosphine ((+)-NMDPP).The two diastereomers formed were separated by chromatography and treated with carbon-monoxide to give the corresponding optically active Fe(CO)3 complexes.The circular dichroism spectra are discussed.The absolute configuration of the planar chirality element in the two diastereomers has been determined by an X-ray diffraction study.