383382-82-9

Upstream product

• 66476-02-6 1-(4-hydroxy-3-methoxyphenyl)-2-phenylethan-1-one 
• 873296-37-8 acetic acid 2-methoxy-4-phenylacetyl-phenyl ester 
• 383383-05-9 1-(4-hydroxy-3-methoxy-2-nitro-phenyl)-2-phenyl-ethanone 

Relevant academic research and scientific papers

Synthesis and biological evaluation of a novel series of "ortho-nitrated" inhibitors of catechol-O-methyltransferase

Novel regioisomeric "ortho-nitrated" catechols related to the catechol-O-methyltransferase (COMT) inhibitors BIA 3-202 3 and BIA 3-335 4 were synthesized and biologically evaluated. Changing the position of the nitro group from the "classical" meta- to th

Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them

New compounds of formula I are described: The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders.