66476-02-6

Basic information

• Product Name: Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-2-phenyl-
• CAS NO: 66476-02-6
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Mol File: 66476-02-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-2-phenyl-(66476-02-6)
• EPA Substance Registry System: Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-2-phenyl-(66476-02-6)

Safety Data

• Hazardous Substances Data: 66476-02-6(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 90-05-1 2-methoxy-phenol 
• 100-44-7 benzyl chloride 
• 274925-95-0 1-(4-benzyloxy-3-methoxyphenyl)-2-phenyl-ethanol 
• 121-33-5 vanillin 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 103-80-0 phenylacetyl chloride 
• 4112-89-4 2-methoxyphenyl 2-phenylacetate 
• 274925-96-1 1-(4-benzyloxy-3-methoxyphenyl)-2-phenyl-ethanone 
• 73049-08-8 4-(1-Hydroxy-2-phenyl-ethyl)-2-methoxy-phenol 

Downstream Products

• 274925-97-2 BIA 3-270 
• 73049-08-8 4-(1-Hydroxy-2-phenyl-ethyl)-2-methoxy-phenol 
• 274925-88-1 1-(3,4-diacetoxy-5-nitrophenyl)-2-phenyl-ethanone 
• 274925-86-9 Nebicapone 
• 383382-82-9 1-(3,4-dihydroxy-2-nitro-phenyl)-2-phenyl-ethanone 
• 383383-05-9 1-(4-hydroxy-3-methoxy-2-nitro-phenyl)-2-phenyl-ethanone 
• 873296-37-8 acetic acid 2-methoxy-4-phenylacetyl-phenyl ester 
• 3391-75-1 2-methoxy-4-((E)-phenylethenyl)phenol 

Relevant articles and documents

A convenient one-pot completely stereoselective synthesis of trans-4-Hydroxystilbenes and its derivatives and X-ray structure of its precursor

The synthesis of E-isomer of 4-Hydroxystilbene and its derivatives 3 by reductive elimination of the carbonyl function in 2-phenyl-1-(4-hydroxyphenyl)ethan-1-one and its derivatives 2 and the X-ray structure of 2a are described.

Synthesis of 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl-ethanone and derivatives as potent and long-acting peripheral inhibitors of catechol-O-methyltransferase

A homologous series of novel nitro-catechol structures (7a-7e) were synthesized and tested as inhibitors of the enzyme catechol-O-methyltransferase (COMT). Increasing chain length was found to have significant impact on both brain penetration and duration

Synthesis of deoxybenzoins

Zinc chloride-phosphoryl chloride is an efficient condensing agent for the preparation of hydroxy(methoxy)deoxybenzoins at room temperature directly from phenols and arylacetic acids.