383672-30-8

Basic information

• Product Name: ethyl 6-[[[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-5-(2,3-dimethoxyphenyl)-7-chloro-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl]amino]-2-pyridinecarboxylate
• Synonyms: ethyl 6-[[[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-5-(2,3-dimethoxyphenyl)-7-chloro-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl]amino]-2-pyridinecarboxylate
• CAS NO: 383672-30-8
• Molecular Weight: 668.143
• Mol File: 383672-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 6-[[[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-5-(2,3-dimethoxyphenyl)-7-chloro-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl]amino]-2-pyridinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-[[[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-5-(2,3-dimethoxyphenyl)-7-chloro-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl]amino]-2-pyridinecarboxylate(383672-30-8)
• EPA Substance Registry System: ethyl 6-[[[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-5-(2,3-dimethoxyphenyl)-7-chloro-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl]amino]-2-pyridinecarboxylate(383672-30-8)

Safety Data

• Hazardous Substances Data: 383672-30-8(Hazardous Substances Data)

Upstream product

• 383661-55-0 2-[(3R,5S)-1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetic acid 
• 69142-64-9 ethyl 6-aminopicolinate 
• 383653-04-1 (3R,5S)-N-propanesulfonyl-1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetamide 

Relevant articles and documents

Benzoxazepinones and their use as squalene synthase inhibitors

There is disclosed a compound represented by the formula [I]: wherein R1 is optionally substituted 1-carboxyethyl group, optionally substituted alkyl-sulfonyl group, optionally substituted (carboxy-cycloalkyl)-alkyl group, -X1-X2-Ar-X3-X4-COOH (wherein X1 and X4 are a bond or alkylene group, X2 and X3 are a bond, -O-, -S-, Ar is divalent aromatic group etc.), R2 is alkyl group optionally substituted with alkanoyloxy group and/or hydroxy group, R3 is alkyl group, and W is halogen atom, etc., or a salt thereof. The compound has the cholesterol lowering activity and the triglyceride lowering activity and is useful for preventing and/or treating hyperlipidemia.