38426-49-2

Upstream product

• 110-91-8 morpholine 
• 1483-82-5 phenylethynyl chloride 

Downstream Products

• 38426-52-7 6,6-Dicyan-2-morpholino-1,3,4-triphenylfulven 
• 115943-74-3 1-Morpholino-2-phenyl-4,4-bis(phenylsulfonyl)-1-cyclobuten 
• 131497-57-9 6-Morpholin-4-yl-5-phenyl-2-p-tolyl-[1,4,3]oxathiazine 4-oxide 
• 129967-76-6 (S)-2-(2'-nitrocyclohexenyl)-1-phenylethan-1-one 
• 129967-72-2 (1'R,3'S)-2-<3'-methoxymethoxy)-2'-nitrocyclohexyl>-1-phenylethan-1-one 
• 131497-58-0 C₁₂H₁₃NO₃S 
• 105140-77-0 (E)-N-(1-Morpholino-2-phenyl-2-sulfinylethyliden)tosylamid 
• 73442-19-0 3-Morpholino-2,4,5-triphenyl-2,4-cyclopentadien-1-on 
• 115592-45-5 2-Morpholino-3-phenyl-5-(p-tolylsulfinyl)furan 
• 17123-83-0 N-(phenylacetyl)morpholine 
• 115592-66-0 (Z)-3-(Morpholinocarbonyl)thiozimtsaeure-S-(p-tolyl)ester 
• 115592-57-9 2-Morpholino-3-phenyl-5-(p-tolylsulfonyl)furan 

Relevant academic research and scientific papers

Low-energy pathway for Pauson-Khand reactions: Synthesis and reactivity of dicobalt hexacarbonyl complexes of chiral ynamines

A family of dicobalt hexacarbonyl complexes of 1-(dialkylamino)-2-(trimethysilyl)acetylenes (3a-f) derived both from achiral and chiral amines [a, morpholine; b, (S)-2-methoxymethylpyrrolidine; c, (2R,5R)-2,5-bis(methoxymethyl)pyrrolidine; d, (±)-trans-2,5-bis(benzyloxymethyl)pyrrolidine; e, (2R,5R)-2,5-dimethylpyrrolidine; f, (S)-(α-methylbenzyl)benzylamine] has been prepared by a one-stage process from dichloroacetylene. The methanolysis at room temperature of these complexes (MeOH/K2CO3) induces the selective cleavage of the carbon-silicon bond, leading to the thermally unstable terminal ynamine complexes 12a-f. The Pauson-Khand reaction of 12a-f with strained olefins (norbornadiene and norbornene) takes place at unprecedentedly low temperatures (-35 °C) in the absence of chemical promoters. Diastereoselectivities of up to 94:6 are recorded in these reactions with the ynamine complexes derived from C2 symmetrical chiral auxiliaries (12c,d). The high reactivity depicted by terminal ynamines in the Pauson-Khand reaction has been analyzed by theoretical semiempirical procedures [PM3(tm)] and with density functional theory (VWN/B88), and appears to reflect an easy CO loss from the ynamine-dicobalt hexacarbonyl complexes.

α-Sulfinylamidines by the Reaction of Ynamines with N-(Sulfinyl)arenesulfonamides

in spite of very different substitution the ynamines 1a-q react with the N-(sulfinyl)arenesulfonamides 2a-c to give the α-sulfonylamidines 4.In on e case we succeeded to isolate both of the configutrtion isomers (E- and Z-4i).The structure of the sulfines 4 is confirmed by spectroscopic data and by some reactions: hydrolysis, photolysis, oxidation, and reaction with 2,3-dimethyl-1,3-butadiene of some sulfines 4 furnish the analogous methylene compounds 5 (exception 6), the 2-oxoamidines 7, and the Diels-Alder adducts 8.