384342-31-8Relevant academic research and scientific papers
Total synthesis and stereochemical assignment of (±)-sorbiterrin A
Qi, Chao,Qin, Tian,Suzuki, Daisuke,Porco, John A.
, p. 3374 - 3377 (2014)
A concise, biomimetic approach to sorbiterrin A has been developed employing consecutive Michael additions of a 4-hydroxypyrone to a sorbicillinol derivative and silver nanoparticle-mediated bridged aldol/dehydration to construct the [3.3.1] ring system. The relative stereochemistry of sorbiterrin A was unambiguously confirmed by X-ray crystallographic analysis.
The Synthesis of Indan-1-ones and Isocoumarins
Carter, Rachel H.,Garson, Mary J.,Hill, Robert A.,Staunton, James,Sunter, David C.
, p. 471 - 479 (2007/10/02)
A flexible synthetic route leading via indan-1-ones to variously methylated and oxygenated isocoumarins is described.The indanones are prepared by alternative routes involving intramolecular Friedel-Crafts cyclisation of arylpropionic acids or pericyclic ring closure of acrylophenones.The influence of substitution on the rate of the pericyclic reaction is assessed.
