38443-50-4

Upstream product

• 108-98-5 thiophenol 
• 4165-57-5 bromobenzene-d5 

Downstream Products

• 64168-46-3 Benzolsulfenanilid-2,3,4,5,6-d⁽⁵⁾ 
• 156268-45-0 N-(Phenylthio-d5)-7-tert-butyl-1-aminopyrene 
• 64168-53-2 4'-Nitrobenzolsulfenanilid-2,3,4,5,6-d5 
• 64168-50-9 4'-Acetyl-benzolsulfenanilid-2,3,4,5,6-d5 
• 74282-77-2 Benzene-2,3,4,5,6-d5-sulfenyl chloride 

Relevant academic research and scientific papers

DIFLUOROHALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES, METHODS OF PREPARATION, AND USES THEREOF

The present invention relates to methods for preparing a variety of difluorohaloallylamine derivatives. The present invention also relates to novel difluorohaloallylamine derivatives that are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for the treatment of a variety of indications, e.g., fibrosis, cancer and/or scarring in human subjects as well as in pets and livestock. In addition, the present invention relates to pharmaceutical compositions containing these compounds, as well as uses thereof.

Deuterium-containing azacyclo-dione compound for treatment of influenza

The invention provides a deuterium-containing azacyclo diketone compound, which is a compound represented by the following structural formula or a pharmaceutically acceptable salt thereof, has proliferation inhibition activity on influenza (influenza) viruses, and particularly inhibits influenza virus proliferation by inhibiting influenza-related cap-dependent endonuclease, so that influenza is treated.

Efficient and selective Pt/C-catalyzed H-D exchange reaction of aromatic rings

An effective and applicable deuteration method for aromatic rings using Pt/C-D2O-H2 system was established. Especially, phenol was fully deuterated even at room temperature, and other electron-rich aromatic nuclei were efficiently deuterated under mild conditions. The scope and limitations of the presence method and its application to the synthesis of deuterium-labeled biologically active compounds and deuterium-labeled building blocks for practical multi-gram scale syntheses are reported. 2008 The Chemical Society of Japan.

The endocyclic restriction test: The geometries of nucleophilic substitutions at sulfur(VI) and sulfur(II)

(Chemical Equation Presented) The trajectories for nucleophilic substitutions at sulfur(VI) and sulfur(II) have been investigated by the endocyclic restriction test. On the basis of double-labeling experiments, the sulfur(VI) transfer in the conversion of 1 to 2 is found to be intramolecular, while the sulfur(VI) transfer in the conversion of 3 to 4 and the sulfur(II) transfer in the conversion of 5 to 6 are found to be intermolecular. These results are taken to be consistent with transition structures for these sulfur transfer reactions which require a large angle between the entering and leaving group, a geometry analogous to apical group positions in trigonal bipyramidal transition states.