38446-21-8

Usage

Uses

Used in Flavor and Fragrance Industry:
Ethyl 2-(ethylamino)benzoate is used as a flavoring agent for its fruity grape aroma, adding a pleasant taste to various food and beverage products. Its medium strength odor and floral type fragrance also make it a suitable candidate for use in the perfumery and cosmetics industry, where it can be used to create captivating and long-lasting scents.
Used in Pharmaceutical Industry:
Ethyl 2-(ethylamino)benzoate can be utilized as an active pharmaceutical ingredient or as a component in the development of new drugs. Its unique chemical properties may contribute to the treatment or management of specific medical conditions, making it a valuable asset in the pharmaceutical sector.
Used in Chemical Research:
Due to its distinct chemical properties, ethyl 2-(ethylamino)benzoate can be employed in various research applications, such as the synthesis of new compounds, the study of chemical reactions, or the development of novel materials. Its versatility in this field can lead to advancements in science and technology.

InChI:InChI=1/C11H15NO2/c1-3-12-10-8-6-5-7-9(10)11(13)14-4-2/h5-8,12H,3-4H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 89-50-9 2-(ethylamino)benzoic acid 
• 74-96-4 ethyl bromide 
• 37960-65-9 potassium anthranilate 
• 64-67-5 diethyl sulfate 
• 91157-24-3 N-Ethyl-3-ethoxy-2,1-benzisoxazoline 
• 31767-67-6 N-Ethylanthranilium fluoroborate 
• 201230-82-2 carbon monoxide 
• 103-69-5 N-ethyl-N-phenylamine 
• 62-53-3 aniline 
• 3422-01-3 tert-butyl phenylcarbamate 
• 210285-26-0 ^tertbutylethyl(phenyl)carbamate 

Downstream Products

• 99105-38-1 2-[(2-Chloro-acetyl)-ethyl-amino]-benzoic acid ethyl ester 
• 52851-60-2 ethyl 1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate 

Relevant academic research and scientific papers

Palladium-catalyzed oxidative carbonylation of aromatic C-H bonds of N -alkylanilines with CO and alcohols for the synthesis of o -aminobenzoates

A Pd(II)-catalyzed C-H monocarbonylation of N-alkylanilines for the synthesis of o-aminobenzoates has been developed. Various aliphatic alcohols and phenol were tolerated in the reaction to afford the corresponding o-aminobenzoates in good yields under mild balloon pressure of CO.

CONVENIENT SYNTHESIS OF ESTERS OF 2-PYRROLECARBOXYLIC ACID AND OF PYRIDINECARBOXYLIC ACIDS BY SOLID-LIQUID PHASE TRANSFER CATALYSIS WITHOUT ADDED SOLVENT

By reaction of aromatic K-carboxylates having nucleophilic N-atom in solid-liquid phase transfer catalysis (PTC) conditions without added solvent (catalyst : tetraalkylammonium halide) with alkylating reagents, the corresponding esters are prepared.By a judicious choice of experimental conditions, the amounts of N-alkylated products can be lowered.From 2-pyrrolecarboxylic acid, the three isomers of pyridinecarboxylic acid and o-aminobenzoic acid, corresponding esters of ethyl, benzyl, n-octyl and n-cetyl, generally are obtained with good yields.

Reactions of Anthranilium Salts with Nucleophiles: Adduct Formation and Rearrangement

3-Unsubstituted anthranilium salts 1 react with alcohols in the presence of bases to yield adducts 5 which rearrange to the esters 4 when refluxed in xylene.Similar processes involving 1 and cyanide or azide also have been observed.Evidence favoring benzoazetinones 2 as rearrangement intermediates is presented.The chemistry of 1 with phosphines and phosphites is also described.For example, treatment of 1c with trimethyl phosphite yields the rearranged adduct salt 14 which cleaves to the acyl phosphonate 15 when treated with triethylamine.