38449-51-3

Usage

Uses

Used in Corrosion Inhibition:
3-tert-Butyl-1H-1,2,4-triazole-5-thiol is used as a corrosion inhibitor for its ability to form protective films on metal surfaces, thereby preventing corrosion and extending the service life of metal components.
Used in Polymer Stabilization:
In the polymer industry, 3-tert-Butyl-1H-1,2,4-triazole-5-thiol is used as a stabilizer to protect polymers from degradation caused by heat, light, and oxygen, ensuring their durability and performance over time.
Used as a Pharmaceutical Intermediate:
3-tert-Butyl-1H-1,2,4-triazole-5-thiol serves as a pharmaceutical intermediate, contributing to the synthesis of various drugs and therapeutic agents.
Used in Coordination Chemistry:
As a ligand in coordination chemistry, 3-tert-Butyl-1H-1,2,4-triazole-5-thiol is used to form coordination complexes with metal ions, which have potential applications in catalysis, materials science, and sensor development.
Used in Antifungal and Antimicrobial Applications:
3-tert-Butyl-1H-1,2,4-triazole-5-thiol is used as an antifungal and antimicrobial agent due to its ability to inhibit the growth of fungi and bacteria, making it a valuable component in various sanitizing and preservation formulations.

InChI:InChI=1/C6H11N3S/c1-6(2,3)4-7-5(10)9-8-4/h1-3H3,(H2,7,8,9,10)

Upstream product

• 42826-42-6 pivalohydrazide 
• 1147550-11-5 ammonium thiocyanate 
• 3282-30-2 pivaloyl chloride 
• 79-19-6 thiosemicarbazide 
• 123-91-1 1,4-dioxane 

Relevant academic research and scientific papers

3-Mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors

The production of β-lactamases is an effective strategy by which pathogenic bacteria can develop resistance against β-lactam antibiotics. While inhibitors of serine-β-lactamases are widely used in combination therapy with β-lactam antibiotics, there are no clinically available inhibitors of metallo-β-lactamases (MBLs), and so there is a need for the development of such inhibitors. This work describes the optimisation of a lead inhibitor previously identified by fragment screening of a compound library. We also report that thiosemicarbazide intermediates in the syntheses of these compounds are also moderately potent inhibitors of the IMP-1 MBL from Pseudomonas aeruginosa. The interactions of these inhibitors with the active site of IMP-1 were examined using in silico methods.

N,N-dialkyl-N′-chlorosulfonyl chloroformamidines in heterocyclic synthesis. VI the preparation of some fused [1,4,2,6]dithiadiazine dioxides

N,N-Dialkyl-N′-chlorosulfonylchloroformamidines 1 were treated with 2-mercaptobenzimidazoles 2 to give [1,4,2,6]dithiadiazino[2,3-a]benzimidazole 1,1-dioxides 3. 3-Mercapto[1,2,4]triazoles 5 afforded [1,2,4]triazolo[2,3-b][1, 4,2,6]dithiadiazine 1,1-dioxides 6 and [1,2,4]triazolo[4,3-b][1,4,2,6] dithiadiazine 1,1-dioxides 7. These products are derivatives of new or very rare heterocycles. CSIRO 2008.

1-dimethylcarbamoyl-3-t-butyl-5-substituted-1H-1,2,4-triazoles

This invention relates to 1-dimethylcarbamoyl-3-t-butyl-5-(carboalkoxy)-alkylthio-1H-1,2,4-triazoles as defined herein, compositions containing those compounds and methods of use.

1-N,N-Dimethylcarbamyl-3-tert.butyl-5-methylthio-1,2,4-triazole

Insects of the orders Coleoptera and Orthoptera and corn rootworms in particular are selectively killed in the presence of living plants by applying to the locus of the insects an effective amount of 1-N,N-dimethylcarbamyl-3-tert.butyl-5-methylthio-1,2,4-triazole. sp This application is a continuation-in-part of copending U.S. Ser. No. 662,171 filed Mar. 1, 1976, now U.S. Pat. No. 4,066,774.

5-Substituted-3-fluorosulfonyl-4H-1,2,4-triazoles and use as insecticides and miticides

New fluorosulfonyltriazole compounds which are useful as miticides and inseciticides have the general structural formula STR1 and tautomeric forms thereof, in which R is hydrogen, C1 to C7 alkyl, alkoxyalkyl, phenoxyalkyl, benzyl, phenyl or C3 to C6 cycloalkyl.

Carbamyltriazole insecticides

Insects of the orders Diptera, Coleoptera, Orthoptera and Lepidoptera are killed in the presence of living plants by applying to the locus of the insects an effective amount of a compound having the structural formula STR1 in which R is 2-propynyl, allyl, 2-bromoallyl, 2-chloroallyl, 2-methylallyl, 1-methylallyl or 2,3,3-trichloroallyl and R' is tert.butyl, propyl, cyclopropyl, isopropyl or 1-methylpropyl.

1-Dimethylcarbamyl-3-branched alkyl-1,2,4-triazol-5-yl-(N-substituted) sulfonamides and use as insecticides

Triazolylsulfonamides of a limited class are substantially non-phytotoxic and are useful as insecticides. For example 1-N,N-dimethylcarbamyl-3-tert.butyl-1,2,4-triazol-5-yl-N,N-dimethylsulfonamide is effective in aphid control, both by foliar application and systemically.