38461-29-9

Usage

Uses

Used in Agricultural Industry:
2,4-Dichloro-1-(2-nitrophenoxy)benzene is used as a herbicide precursor for controlling broadleaf weeds in various agricultural settings. Its application is aimed at enhancing crop yield by reducing competition from unwanted plants.
Used in Chemical Synthesis:
In the chemical industry, 2,4-Dichloro-1-(2-nitrophenoxy)benzene is utilized as an intermediate in the synthesis of various pesticides and herbicides, contributing to the development of products designed to protect crops from pests and weeds.
However, due to its toxicity and potential for bioaccumulation in the food chain, 2,4-Dichloro-1-(2-nitrophenoxy)benzene is classified as a potential environmental and human health hazard. As a result, its use and disposal are strictly regulated in many countries to mitigate risks associated with its presence in the environment and to ensure the safety of both ecosystems and human populations.

InChI:InChI=1/C12H7Cl2NO3/c13-8-5-6-11(9(14)7-8)18-12-4-2-1-3-10(12)15(16)17/h1-7H

Upstream product

• 88-73-3 2-Chloronitrobenzene 
• 120-83-2 2,4-dichlorophenol 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 55476-44-3 HSP₇ 
• 26306-64-9 2,4-dichloro-1-(2-aminophenoxy)benzene 
• 1479164-77-6 1-(2-azidophenoxy)-2,4-dichlorobenzene 
• 1479164-78-7 ethyl 1-(2-(2,4-dichlorophenoxy)phenyl)-1H-1,2,3-triazole-4-carboxylate 

Relevant academic research and scientific papers

Design, synthesis and nematicidal activitives of trifluorobutene amide derivatives against Meloidogyne incognita

Plant parasitic nematodes have always been a pressing problem in the field of plant protection. Well-established chemical nematicides, especially organophosphorus and carbamates are the most used products for nematode control worldwide. Due to long-term overuse, they have developed serious resistance and new innovative solutions are urgently required. In this study, thirty-one novel trifluorobutene amide derivatives were designed and synthesized, and their nematicidal activities were determined. Three different synthetic methods have been developed for the final amidation reaction enabling the successfully syntheses of the target compounds independently from the nucleophilicities of the substrate amino group. Most target compounds showed good nematicidal activity in our in vitro test. Among all the compounds, compounds A8 and A23 exhibited excellent nematicidal activity against Meloidogyne incognita, their LC50 values are 2.02 mg L?1 and 0.76 mg L?1, respectively. In particular, compound A23 has found to be almost as active as the commercial nematicide fluensulfone. Furthermore, most compounds gave full control (100% inhibition) of M. incognita at 40 mg L?1 in the in vivo tests in sandy soil, the best compounds were further investigated for in vivo activity in matrix soil. Among the compound tested, compound A8 showed excellent in vivo nematicidal activity. At a concentration of 5 mg L?1 still 56% inhibition was observed. The results of our study indicate that compound A8 possesses excellent in vitro and in vivo nematicidal activity, and can be considered as promising lead molecule for further modification.

Pyrazinamide compounds, preparation method and application thereof as well as bactericide

The invention relates to the field of pesticide bactericides and discloses pyrazinamide compounds, a preparation method and an application thereof as well as a bactericide. The compounds have the structure shown in formula (I). The pyrazinamide compounds with the novel structure are designed by introducing pyrazine ring fragments in Pyradiflumid and diphenyl ether fragments with wide bioactivity,and the pyrazinamide compounds can be used as novel SDHIs (succinate dehydrogenase inhibitors) or bactericides.

A bactericide composition and the preparation and use thereof (by machine translation)

The invention relates to the field of agricultural fungicide, discloses a fungicide composition, a preparation of the fungicide composition and application of the preparation, and in particular relates to a fungicide composition for preventing gray mold, a preparation of the fungicide composition and application of the preparation. The fungicide composition contains fludioxonil and pyrazolecarboxamide compounds, which have the weight ratio of 1:1000-1000:1. The pesticide preparation prepared from the fungicide composition is used for preventing gray mold, has treatment and protection functions, has good synergism, has good fungicidal effect, and is safe to crops, and the application frequency of the pesticide preparation can be reduced.

A bactericide composition and the preparation and use thereof

The invention relates to the field of agricultural bactericides and discloses a bactericide composition and a preparation as well as application thereof, and particularly relates to a bactericide composition used for preventing and treating rice sheath blight diseases and a preparation as well as application thereof. The composition is a bactericide composition containing a pyrazole amide type compound and validamycin. A pesticide preparation processed by adopting the composition can be used for preventing and treating the rice sheath blight diseases, has treatment and protection effects, has a good synergistic effect, and has the advantages of safety to crops and the like.

PLANT CIRCADIAN RHYTHM REGULATING AGENT

PROBLEM TO BE SOLVED: To provide a plant circadian rhythm regulating agent, and a more simple and convenient plant circadian rhythm regulating method. SOLUTION: A plant circadian rhythm regulating agent contains a heterocycle-containing compound represented by the general formula (1) or an agriculturally acceptable salt, hydrate or solvate thereof as an active ingredient. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Design, synthesis and antifungal activity of novel furancarboxamide derivatives

Twenty-seven novel furancarboxamide derivatives with a diphenyl ether moiety were synthesized and evaluated for their antifungal activity against Rhizoctonia solani, Botrytis cirerea, Valsa Mali and Sphaceloma ampelimum. Antifungal bioassay results indicated that most compounds had good or excellent fungicidal activities for R. solani and S. ampelimum at 20 mg L-1. Among synthesized compounds, compound 18e showed a greater inhibitory effect against S. ampelimum, with half maximal effective concentration (EC50) values of 0.020 mg L-1. This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.

DIARYL SUBSTITUTED HETEROAROMATIC COMPOUNDS

The invention relates to heterocyclic derivatives, to the use of said derivatives in treating a range of metabolic diseases and other conditions mediated by agonism of the G-protein coupled bile acid GPBAR1/TGR5 receptor, to compositions and formulations containing said derivatives, processes for their preparation and methods of delivery.

NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS

The present invention relates to new sulfonamide derivatives of formula (I), wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.

NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS

The present invention relates to new sulfonamide derivatives of formula (I), wherein R1 -R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.

NEW BENZAMIDE DERIVATIVES AS BRAD YKININ ANTAGONISTS

The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I), wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.