38470-69-8

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 27664-11-5 1-(4-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)prop-2-en-1-one 
• 1160926-29-3 3-[3-(4-methoxyphenyl)-4-(morpholin-4-ylmethyl)-4,5-dihydro-isoxazol-5-yl]-1H-indole 
• 1160926-25-9 3-[3-(4-methoxyphenyl)-4-(piperidin-1-ylmethyl)-4,5-dihydro-isoxazol-5-yl]-1H-indole 
• 119550-11-7 3-(3-indolyl)-3-(1,2,4-triazol-1-yl)-1-(4-methoxyphenyl)propan-1-ol 
• 119549-95-0 3-(3-indolyl)-3-(1,2,4-triazol-1-yl)-1-(4-methoxyphenyl)propan-1-one 
• 69022-95-3 5-(1H-indol-3-yl)-3-(4-methoxyphenyl)-4,5-dihydroisoxazoline 
• 1164510-94-4 3-[1-(2-hydroxy-3-morpholin-4-yl-propyl)-1H-indol-3-yl]-1-(4-methoxy-phenyl)-propenone 

Relevant academic research and scientific papers

Solvent effect profiles of absorbance and fluorescence spectra of some indole based chalcones

The photophysical properties of a series of 3-(1' H-Indol-3′-yl)-1- phenylprop-2-en-1-one and its derivatives (indole chalcones) were studied in different solvents. Solvent effects on the absorption and fluorescence spectra were quantified using Reichardt

Synthesis and evaluation of chalcone derivatives as novel sunscreen agent

Ultraviolet (UV) irradiation is a serious problem for skin health thus the interest in the research to develop sunscreen agent has been increasing. Chalcone is a promising compound to be developed as its chromophore absorbs in the UV region. Therefore, in

Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids

Sulfonamide is one of the most promising classes of classical carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. A novel series of indolylchalcones incorporating benzenesulfonamide-1,2,3-triazole (6a-q) has been synthesized by click chemistry reaction and in

Synthesis and antioxidant activity of a new class of pyrazolyl indoles, thiazolyl pyrazolyl indoles

A new class of bis and tris heterocycles–pyrazolyl indoles and thiazolyl pyrazolyl indoles were prepared from the Michael acceptor (E)-3-(1H-indol-3-yl)-1-arylprop-2-en-1-ones by ultrasound irradiation technique and tested for antioxidant activity. The th

Synthesis, Characterisation, Molecular Docking, Anti-microbial and Anti-diabetic Screening of Substituted 4-indolylphenyl-6-arylpyrimidine-2-imine Derivatives

The purpose of the research is to synthesise a novel series of (E)-2-(4-(1H-indol-3-yl)-6-p-substituted phenylpyrimidin-2-yl)dimethylguanidine derivatives since 3-(1H-indol-3-yl)-1-p-substituted phenylprop-2-en-1-one and evaluate their molecular docking s

An efficient method for the synthesis of isoxazolines under microwave irradiation and solvent-free conditions

A facile method for the synthesis of new isoxazoline derivatives are being reported starting from substituted 1-(1H-indol-3-yl)-3-(substituted aryl)-prop-1-en-3-ones and hydroxylamine hydrochloride under solvent free conditions and microwave irradiation.

Synthesis and biological evaluation of indolyl chalcones as antitumor agents

A series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer activity against three human cancer cell lines. Compounds 3b-d, 3h, 3j, 3l, 3m, 4g, and 4j showed significant cytotoxicity, particularly, indolyl chalcones 3l and 3

Design and synthesis of 3-[3-(substituted phenyl)-4-piperidin-1-ylmethyl/- 4-morpholin-4-ylmethyl-4,5-dihydro-isoxazol-5-yl]-1H-indoles as potent anti-inflammatory agents

The synthesis of new indole derivatives bearing isoxazoline moiety (3a-d and 4a-d) has been described. IR, 1H NMR, and mass spectral data supported the structures of synthesized compounds. The compounds were tested in vivo for their anti-inflam

Solution phase combinatorial synthesis and screening of mini libraries of arylchalcones for antibacterial activity

The solution-phase combinatorial synthesis of aryl chalcones was studied by synthesizing a 6x4 array mini library. The mini libraries of chalcones were synthesized by condensation of 4-substituted acetophenones and various aryl/heteroaryl carbaldehydes. A

Synthesis of substituted indole derivatives as a new class of antimalarial agents

A series of substituted indole derivatives were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 24 compounds synthesized six compounds have shown MIC of 1 μg/mL. These compounds are in vitro several fol