69022-95-3

Upstream product

• 38470-69-8 3-(1'H-indol-3'-yl)-1-(4-methoxyphenyl)-prop-2-en-1-one 
• 487-89-8 Indole-3-carboxaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 1160926-29-3 3-[3-(4-methoxyphenyl)-4-(morpholin-4-ylmethyl)-4,5-dihydro-isoxazol-5-yl]-1H-indole 
• 1160926-25-9 3-[3-(4-methoxyphenyl)-4-(piperidin-1-ylmethyl)-4,5-dihydro-isoxazol-5-yl]-1H-indole 

Relevant academic research and scientific papers

An efficient method for the synthesis of isoxazolines under microwave irradiation and solvent-free conditions

A facile method for the synthesis of new isoxazoline derivatives are being reported starting from substituted 1-(1H-indol-3-yl)-3-(substituted aryl)-prop-1-en-3-ones and hydroxylamine hydrochloride under solvent free conditions and microwave irradiation.

Design and synthesis of 3-[3-(substituted phenyl)-4-piperidin-1-ylmethyl/- 4-morpholin-4-ylmethyl-4,5-dihydro-isoxazol-5-yl]-1H-indoles as potent anti-inflammatory agents

The synthesis of new indole derivatives bearing isoxazoline moiety (3a-d and 4a-d) has been described. IR, 1H NMR, and mass spectral data supported the structures of synthesized compounds. The compounds were tested in vivo for their anti-inflam