38477-80-4

Upstream product

• 13920-94-0 bis(2-methoxyphenyl)disulfide 
• 106-95-6 allyl bromide 
• 7217-59-6 2-Methoxybenzenethiol 

Downstream Products

• 113943-96-7 cis 3-(3,4-dichlorophenyl)-3-<(1H-imidazol-1-yl)methyl>-5-<<(2-methoxyphenyl)thio>methyl>-2-methylisoxazolidine 
• 1064703-89-4 C₁₀H₁₁⁽²⁾HOS 
• 83862-67-3 1-<(2-Methoxyphenyl)thio>-1-(trimethylsilyl)-2-propene 
• 83876-14-6 (3β,20S,23Z)-3,20-Dihydroxy-21-methoxy-24-<(2-methoxyphenyl)thio>-24-(trimethylsilyl)-5β-chol-23-ene 
• 83897-12-5 S-(2-Methoxyphenyl) (3β,20S,22E)-3,20-Dihydroxy-21-methoxy-5β-chol-22-ene-24-thioate 

Relevant academic research and scientific papers

Synthesis of sulfimides and N-Allyl-N-(thio)amides by Ru(II)catalyzed nitrene transfer reactions of N-acyloxyamides

The N-acyloxyamides were employed as effective N-acyl nitrene precursors in reactions with thioethers under the catalysis of a commercially available Ru(II) complex, from which a variety of sulfimides were synthesized efficiently and mildly. If an allyl group is contained in the thioether precursor, the [2,3]-sigmatropic rearrangement of the sulfimide occurs simultaneously and the N-allyl-N-(thio)amides were obtained as the final products. Preliminary mechanistic studies indicated that the Ru-nitrenoid species should be a key intermediate in the transformation.

Hemin Catalyzed Dealkylative Intercepted [2, 3]-Sigmatropic Rearrangement Reactions of Sulfonium Ylides with 2, 2, 2-Trifluorodiazoethane

A dealkylative intercepted [2, 3]-sigmatropic rearrangement reaction of allylic sulfides with 2, 2, 2-trifluorodiazoethane (CF3CHN2) is reported, the commercially available and biocompatible catalyst hemin was found to efficiently catalyze this transformation across a diverse set of allylic sulfides with in situ generated CF3CHN2, providing excellent yields (up to 99%) under mild condition without inert gas protection. In addition, CF3CHN2 exhibited unique reactivity toward this process compared with other frequently used diazo reagents. This work expands the range of carbene-mediated transformations catalyzed by hemin and introduces a concise and general strategy for exploiting new possibility of reactions concerning organosulfides. (Figure presented.).

Selective O-deallylation of o-allyloxyanisoles

o-Allyloxyanisoles are selectively and easily deallylated by treatment with sec- or tert-butyllithium at low temperature. The reaction is proposed to proceed through a tandem intermolecular carbolithiation-β;-elimination process, which can also be considered an SN2′ attack of the organolithium on the allyl ether.

Ytterbium metal promoted allylation of disulfides with allyl bromide

In the presence of a catalytic amount of methyliodide, ytterbium metal can promote the reductive cleavage of the S-S bond in disufides 1 to give ytterbium thiolates 2 which then react with allyl bromide to form the corresponding allylic sulfides 3 in good yields under mild and neutral conditions.