38489-93-9

Basic information

• Product Name: 2-(hydroxyimino)-5,6-(methylenedioxy)-1-indanone
• Synonyms: 2-(hydroxyimino)-5,6-(methylenedioxy)-1-indanone;5H-Indeno[5,6-d]-1,3-dioxole-5,6(7H)-dione 6-OxiMe;6-(HydroxyiMino)-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-one
• CAS NO: 38489-93-9
• Molecular Formula: C₁₀H₇NO₄
• Molecular Weight: 205
• Product Categories: Amines;Aromatics;Heterocycles;Neurochemicals;Amines, Aromatics, Heterocycles, Neurochemicals
• Mol File: 38489-93-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility: DMSO
• CAS DataBase Reference: 2-(hydroxyimino)-5,6-(methylenedioxy)-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(hydroxyimino)-5,6-(methylenedioxy)-1-indanone(38489-93-9)
• EPA Substance Registry System: 2-(hydroxyimino)-5,6-(methylenedioxy)-1-indanone(38489-93-9)

Safety Data

• Hazardous Substances Data: 38489-93-9(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

Different sources of media describe the Uses of 38489-93-9 differently. You can refer to the following data:
1. 5H-Indeno[5,6-d]-1,3-dioxole-5,6(7H)-dione 6-oxime can be used in the preparation of nonneurotoxic tetralin, indan analogues and in the total synthesis of Papilistatin. Papilistatin is a unique phenanthrene-1,10-dicarboxylic acid having good anticancer and antibacterial activity.
2. Can be used in the preparation of nonneurotoxic tetralin and indan analogues.

Upstream product

• 2815-95-4 3-(1,3 benzodioxol-5-yl)propionic acid 
• 68996-81-6 3-benzo[1,3]dioxol-5-yl-propionyl chloride 
• 6412-87-9 5,6-methylenedioxy-1-indanone 
• 2373-80-0 3,4-(methylenedioxy)cinnamic acid 
• 120-57-0 piperonal 
• 110-46-3 isopentyl nitrite 

Downstream Products

• 1294495-52-5 (Z/E)-3-(2-bromo-6-methoxyphenyl)-2-(2-carboxy-4,5-methylenedioxyphenyl)acrylic acid methyl ester 
• 132741-81-2 6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-6-amine 

Relevant articles and documents

Formation of the 5-Benzonaphthopyran System during an Attempted Benzophenanthridine Synthesis

The condensation of the Schiff base 6 with the homophthalic anhydride 7 was used during elaboration of a compound, 9, suitable for closure of the B ring of the benzophenanthridine system.However, treatment of 9 with sodium hydride in THF resulted in formation of 3,4-dimethoxy-5-oxo-7-cyano-9,10-(methylenedioxy)-5-benzonaphthopyran (10) instead of the Dieckmann-Thorpe cyclization product 2.

Synthesis of 4-Aryl-2-benzazepine-1,5-diones by Photocyclization of N-(2-Arylethyl)phthalimides

The photocyclization of N-(2-arylethyl)phthalimides to 4-aryl-2-benzazepine-1,5-diones is described.We found that the presence of electron donating substituents on the aryl ring (as in 10a and b) is necessary for the cyclization process to occur.The procedure also allowed synthesis of 2-benzazepinediones with a carboxylate group at C3 (11c and d) which were obtained as 1:1 mixture of diastereoisomers.The results of irradiating phthalimides 12, which bear an oxygenated substituent at the benzylic position, depended on the nature of the substituent.Attempts to photocyclize N-(indan-2-yl)phthalimides 16 and the electron-rich phthalimide 23 failed.