3850-44-0Relevant academic research and scientific papers
SYNTHESIS OF CHIRAL OLIGOPEPTIDES BY MEANS OF CATALYTIC ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDES
Ojima, Iwao,Yoda, Noriko,Yatabe, Momoko,Tanaka, Toshiyuki,Kogure, Tetsuo
, p. 1255 - 1268 (2007/10/02)
Asymmetric hydrogenation of Ac-ΔTyr(Ac)-(S)-Ala-Gly-OMe (6), Ac-ΔTyr(Ac)-(R)-Ala-Gly-(S)-Phe-OMe (7), Ac-ΔPhe-NH-CH(R)-CH2-OCH2Ph (10), HCO-ΔPhe-(S)-Leu-OMe (16), X-AA-ΔPhe-AA'-OMe ( 5: X=tBOC, CBZ, CF3CO; AA, AA'= α-amino acid ), and t
ETUDE DE LA RACEMISATION INDUITE PAR LA DMAP DANS LES REACTIONS DE COUPLAGE PEPTIDIQUE
Gamet, Jean-Paul,Jacquier, Robert,Verducci, Jean
, p. 1995 - 2002 (2007/10/02)
The scope and limitation for the use of 4-dimethyalmino pyridine (DMAP) as additive to carbodiimides in peptide synthesis are studied and compared with the results obtained with N-hydroxybenzotriazole (HOBt).The activation of N-acylated aminoacids by the
SYNTHESIS OF ENKEPHALIN ANALOGS VIA ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDE BUILDING BLOCKS
Ojima, Iwao,Yoda, Noriko,Yatabe, Momoko
, p. 3917 - 3920 (2007/10/02)
1, D-Ala2, Leu5-OMe>Enkephalin and 1, D-Ala2, Leu5-OMe>Enkephalin were succesfully synthesized by the coupling of dipeptide units and tripeptide units which were readily obt
Octapeptides and methods for their production
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, (2008/06/13)
New octapeptides having the formula Prot Grp-R-Trp-Ser-Tyr-R2 -Leu-Arg-Pro-R3 ; salts thereof; wherein R is Gln, Gln (bzl), His (bzl), Ser (bzl), Pro, Leu, Tyr (bzl), Ile, Cys (bzl) or Phe, R2 is D-Phe, D-Ala, D-Leu, D-Trp, D-Tyr, D-Tyr (Me), D-Ser, D-Met, D-Arg, D-Val, D-His, D-Gln, D-Phs, D-Thr, D-Pro, D-Me5 Phe or D-Asn and R3 is NH2, NH(lower alkyl), N-(lower alkyl)2, NH-benzyl, NHCH2 CH2 N-(lower alkyl)2 or NH-CH2 CH2 SO2 NH-benzyl; methods for their production; certain peptide intermediates and their salts used in the production thereof; and the use of said octapeptides as luteinizing hormone releasing factor antagonists.
Nonapeptides and methods for their production
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, (2008/06/13)
New nonapeptides having the formula Prot Grp-R-Trp-Ser-Tyr-R2 -Leu-Arg-Pro-Gly-R3 ; salts thereof; wherein R is Gln, Gln (bzl), His (bzl), Ser (bzl), Pro, Leu, Tyr (bzl), Ile, Cys (bzl) or Phe, R2 is D-Phe, D-Ala, D-Leu, D-Trp, D-Tyr, D-Tyr (Me), D-Ser, D-Met, D-Arg, D-Val, D-His, D-Gln, D-Phs, D-Thr, D-Pro or D-Asn and R3 is NH2, NH(lower alkyl) or N-(lower alkyl)2, methods for their production; certain peptide intermediates and their salts used in the production thereof; and the use of said nonapeptides as luteinizing hormone releasing factor antagonists.
