38502-01-1

Upstream product

• 67-66-3 chloroform 
• 2497-33-8 4-((4-methylphenyl)azo)phenol 
• 106-49-0 p-toluidine 
• 90-02-8 salicylaldehyde 
• 2028-84-4 p-methylbenzenediazonium chloride 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 1228435-80-0 (E)-(2-hydroxy-5-(p-tolyldiazenyl)phenyl)(phenyl)methanone 

Relevant academic research and scientific papers

Synthesis, crystal structure, DFT calculations, Hirshfeld surfaces, and antibacterial activities of schiff base based on imidazole

A new Schiff base 2 was synthesized by condensation of 2-Hydroxy-5-(p-tolyldiazenyl)benzaldehyde and N(-3-aminopropyl)imidazole, and characterized by IR, 1H NMR, 13C NMR, mass spectroscopy and elemental analysis. Crystal structure of

Receptor with an active methylene group as binding site for extraction of inorganic fluoride ions from seawater

Two new receptors R1 and R2 based on triphenylphosphonium salts with an active methylene group as binding site have been designed and synthesised for the detection of F- ions. The detection limit of these receptors in organic media was found to

Sustainable synthesis of [1]benzopyran azo dyes using CuCr2O4 NPs

In this study, copper chromite nanoparticles (CuCr2O4 NPs) were prepared by a simple hydrothermal method. This nanomaterial was found as an efficient heterogeneous catalyst for the synthesis of a new class of [1]benzopyran azo dyes v

Synthesis of new bis-benzylidene-hydrazides as a sensitive chromogenic sensor for naked-eye detection of CNˉ and AcOˉ ions

Some new bis-benzylidene-hydrazides were synthesized via a condensation reaction of the corresponding azo dyes with adipic acid dihydrazide. All compounds because of the three possible stereoisomers showed four sets of signals in NMR. The anion recognition studies exhibited that the nitro bis-benzylidene-hydrazide derivative acts as a highly sensitive and selective chromogenic sensor for naked-eye detection of CNˉ and AcOˉ ions, with a distinct color change from yellow to blue and yellow to purple, respectively. The limit of detection (LOD) was found for 1d toward CNˉ to be 1.1 μM. The result of the Job's plot indicated stoichiometry of binding between chemosensor and anions is found to be 1:2.

Sensitivity and Resolution Development of Spiropyran-based Molecular Photoswitches

The phenylazo moiety and its donor- and acceptor-substituted derivatives are studied as effective auxochromes to improve their sensitivity and resolution for distinguishing between the spiro (SP; OFF) and mero (ON) forms in molecular photoswitching applications. Thus, 13 azospiropyran derivatives were synthesized and their spectroscopic and photokinetic behaviors were studied. The quality of photochromic reactions of the synthesized photochromic compounds were compared using a dose–response model. Interestingly, by replacing the nitro group in 6-nitrospiropyran (ε = 0.42 × 104 M?1 cm?1) with a simple phenylazo moiety, the SP form is still colorless and the color intensity of the merocyanine (MC) form is improved desirably by extending the conjugation length (1a, ε = 1.35 × 104 M?1 cm?1). The presence of a hydrophilic OH group or a CH3 group at the para position of phenylazo moiety revealed more or less the same photochromic properties as 1a. The OCH3 group substituted at position 6 of the phenylazo moiety at the para position of the azobenzene moiety effectively increased the photochromic properties with the maximum k-value for SP to MC switching. Meanwhile, Cl, Br, COOH, and NO2 groups at the para position of the azobenzene moiety revealed the reduction in photochromic properties compared to 1a.

Synthesis, characterization, and electrochemical study of some novel, azo-containing Schiff bases and their Ni(II) complexes

Five novel azo-azomethine ligands with NN'OS coordination spheres were prepared by reaction of methyl-2-{N-(2′-aminoethane)}-amino-1- cyclopentenedithiocarboxylate (Hcden) with (E)-2-hydroxy-5-(phenyldiazenyl) benzaldehyde and its substituted derivatives

Theoretical investigation of the conformation and hydrogen bonding ability of 5-arylazosalicylaldoximes

Conformations of 5-arylazosalicylaldoximes 6-10 have been predicted from spectral and theoretical studies. The orientation of OH bond is predicted to be anti to CN bond from the PES analysis. The presence of intramolecular hydrogen bonding in oximes 6-10 and their parent aldehydes 1-5 is supported by the additional bond and ring critical points from AIM analysis, hyperconjugative interaction energies determined from NBO analysis and selected geometrical parameters derived from optimized structures. Molecular properties such as dipole moment, polarizability and hyperpolarizabilities for oximes 6-10 and their parent aldehydes 1-5 were also determined by computational studies.

Direct C-H bond arylation of 2-hydroxybenzaldehydes with arylboronic acids via ligand-free palladium catalysis

A mild and efficient ligand-free palladium-catalyzed direct C-H bond arylation reaction was developed to afford 2-hydroxybenzophenones in good to excellent yields from easily available 2-hydroxybenzaldehydes and arylboronic acids. The given reaction provided one of the easiest pathways for accessing 2-hydroxybenzophenones, and a variety of functional groups could be tolerated in this process.

Some polyhydroxy azo-azomethine derivatives of salicylaldehyde: Synthesis, characterization, spectroscopic, molecular structure and antimicrobial activity studies

Some new substituted polyhydroxy azo-azomethine compounds were prepared by reaction of tris(hydroxymethyl)aminomethane with (E)-2-hydroxy-5-(phenyldiazenyl) benzaldehyde and its substituted derivatives. The structures of azo and azo-azomethine compounds were determined by IR, UV-vis, 1H NMR and 13C NMR spectroscopic techniques, and/or X-ray diffraction studies. According to IR spectra, all azo-azomethine compounds adopt keto form in solid state. UV-vis analysis has shown the presence of keto-enol tautomerism in solution for all azo-azomethine compounds, except that for nitro substituted derivative, enol form is dominantly favored in solution. At the same time, above mentioned derivative compounds were studied in vitro for their antimicrobial properties. Among the phenylazosalicylaldehyde series compound tested, 4-phenylazosalicylaldehyde, 4-(3-chlorophenylazo)salicylaldehyde, 4-(2-chlorophenylazo)salicylaldehyde, 4-(4-fluorophenylazo)salicylaldehyde, 4-(3-chlorophenylazo)salicylaldehyde and 4-(4-ethylphenylazo)salicylaldehyde showed a weak antimicrobial activity only against gram positive bacteria. On the contrary, phenylazosalicylaldehyde series compounds were reacted tris(hydroxmethyl)aminomethane, that exhibited a strong antimicrobial activity against gram positive bacteria, yeast and mould. Moreover, while the 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-ylimino]methyl}phenol did not show an inhibition on tested microorganism, the addition of phenyldiazine groups to 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-ylimino]methyl}phenol resulted in a strong increases in antimicrobial activity.

Synthesis and spectroscopic studies of some transition metal complexes of a novel Schiff base ligands derived from 5-phenylazo-salicyladehyde and o-amino benzoic acid

Cu(II), Mn(II), Ni(II), and Zn(II) metal complexes with novel heterocyclic Schiff base derived from 5-phenyl azo-salicyladehyde and o-amino benzoic acid have been synthesized and characterized on the basis of elemental analyses, electronic, IR, and 1H NMR spectra, and also by aid of scanning electron microscopy (SEM), X-ray powder diffraction, molar ratio measurements, molar conductivity measurements, and thermogravimetric analyses. It has been found that the Schiff base behaves as neutral tridentate (ONO) ligand forming chelates with 1:1 (metal:ligand) stoichiometry.