38520-68-2

Usage

Uses

Used in Pharmaceutical Applications:
(6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) is used as a pharmacological agent for its potential role as a dopamine receptor agonist, which may aid in the treatment of addiction and Parkinson's disease. Its interaction with dopamine receptors could provide therapeutic benefits for patients suffering from these conditions.
Used in Pain Management:
In the field of pain management, (6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) is used as an analgesic agent due to its potential pain-relieving properties. This application could be beneficial for patients experiencing various types of pain, offering an alternative treatment option.
Used in Anti-inflammatory Applications:
(6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) is also used as an anti-inflammatory agent, leveraging its potential to reduce inflammation and alleviate symptoms associated with inflammatory conditions. This application could be particularly useful in the treatment of chronic inflammatory diseases.
Used in Research and Development:
In the context of research and development, (6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) serves as a valuable compound for further investigation into its pharmacological properties and potential applications in medicine. Its unique chemical structure and promising characteristics make it an attractive candidate for the development of new drugs and therapies.

Upstream product

• 186581-53-3 diazomethane 
• 525-72-4 (+/-)-salsolinol 
• 91-63-4 2-methylquinoline 
• 34989-82-7 3-methylbenzo[d]isothiazole-1,1-dioxide 
• 4721-98-6 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline 
• 6268-86-6 dimethoxy-6,7 methyl-1 dihydro-3,4 isoquinoleine chlorhydrate 

Downstream Products

• 525-72-4 (+/-)-salsolinol 
• 145160-07-2 1-(3,4-dimethoxyphenyl)-2-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-2-isoquinolinyl)ethanone 
• 110691-51-5 (1S)-2<<(R)-1-phenylethyl>carbamoyl>salsolidine 
• 110691-52-6 (1R)-2<<(R)-1-phenylethyl>carbamoyl>salsolidine 
• 20412-80-0 1-Methyl-2-n-propyl-6,7-dimethoxy-1,2,3,4-tetrahydroisochinolin 
• 101041-08-1 Cyclohexylidene-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-amine 
• 58406-47-6 N-Allylsalsolidine 
• 51918-42-4 6,7-dimethoxy-2-isobutanoyl-1,2,3,4-tetrahydroisoquinoline 
• 36113-36-7 2-Chloro-1-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone 
• 879466-29-2 C₂₀H₂₅NO₂ 
• 490-53-9 (+/-)-carnegine 
• 493-48-1 (S)-salsolidine 
• 508236-97-3 5-(3,4-Dimethoxybenzylamino)-8-(6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ylmethyl)-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine 

Relevant academic research and scientific papers

Vancomycin-iridium (III) interaction: An unexplored route for enantioselective imine reduction

The chiral structure of antibiotic vancomycin (Van) was exploited as an innovative coordination sphere for the preparation of an IrCp* based hybrid catalysts. We found that Van is able to coordinate iridium (Ir(III)) and the complexation was demonstrated by several analytical techniques such as MALDI-TOF, UV, Circular dichroism (CD), Raman IR, and NMR. The hybrid system so obtained was employed in the Asymmetric Transfer Hydrogenation (ATH) of cyclic imines allowing to obtain a valuable 61% e.e. (R) in the asymmetric reduction of quinaldine 2. The catalytic system exhibited a saturation kinetics with a calculated efficiency of Kcat/KM = 0.688 h?1mM?1

METABOLISM OF SALSOLINOL BY TISSUE CULTURES OF SOME PAPAVERACEAE

(+/-)-Salsolinol, a substance possibly inducing Parkinsonism and alcoholism, was transformed into the 6- and 7-O-monomethylated salsolinols by various plant tissue cultures of Papaveraceae.Only 6-O-methylsalsolinol was further N-methylated to provide N-methylisosalsoline.Key Word Index - Corydalis ochotensis; C. opliocarpa; Macleaya cordata; Papaveraceae; tissue cultures; metabolism; isoquinoline alkaloid; salsolinol.

2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics

Analgesic 1,2,3,4-tetrahydroisoquinolines of the formula (1) STR1 wherein R1 and R2 respectively are hydrogen, hydroxy or alkoxy of 1 to 4 carbon atoms, R3 and R4 respectively are hydrogen or alkyl of 1 to 4 car