385374-39-0

Basic information

• Product Name: 2,3,5-tri-O-benzyl-4-O-methanesulfonyl-D-ribose dibenzyl dithioacetal
• Synonyms: 2,3,5-tri-O-benzyl-4-O-methanesulfonyl-D-ribose dibenzyl dithioacetal
• CAS NO: 385374-39-0
• Molecular Weight: 728.995
• Mol File: 385374-39-0.mol

Chemical Properties

• CAS DataBase Reference: 2,3,5-tri-O-benzyl-4-O-methanesulfonyl-D-ribose dibenzyl dithioacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5-tri-O-benzyl-4-O-methanesulfonyl-D-ribose dibenzyl dithioacetal(385374-39-0)
• EPA Substance Registry System: 2,3,5-tri-O-benzyl-4-O-methanesulfonyl-D-ribose dibenzyl dithioacetal(385374-39-0)

Safety Data

• Hazardous Substances Data: 385374-39-0(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 153439-75-9 2,3,5-tri-O-benzyl-D-ribose dibenzyldithioacetal 

Downstream Products

• 1198761-02-2 (1R,2S,3R,4R)-methanesulfonic acid 2,3-bis-benzyloxy-1-benzyloxymethyl-4-benzylsulfanyl-4-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-butyl ester 
• 1198761-03-3 (1R,2S,3R,4S)-methanesulfonic acid 2,3-bis-benzyloxy-1-benzyloxymethyl-4-benzylsulfanyl-4-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-butyl ester 
• 153541-51-6 benzyl 2,3,5-tri-O-benzyl-1,4-dithio-L-lyxofuranoside 

Relevant articles and documents

Thiosugars. VIII. Preparation of new 4′-thio-L-lyxo pyrimidine nucleoside analogues

Reaction of 1-O-acetyl-2,3,5-tri-O-benzyl-4-thio-L-lyxofuranose with silylated pyrimidine bases and subsequent deprotection with boron tribromide led to 4′-thio-L-lyxo pyrimidine nucleosides. The 5-bromo-6-methyl derivative was prepared from methyl 2,3,5-

A stereoselective approach to nucleosides and 4′-thioanalogues from acyclic precursors

D- and L-nucleosides and analogues thereof, including the 4′-thionucleoside series, are one of the most important biological and pharmaceutically active classes of compounds. A novel approach to their synthesis from chiral acyclic thioaminal, bearing the nucleobase, is described.