385396-74-7Relevant academic research and scientific papers
Anthranilic acid amides: A novel class of antiangiogenic VEGF receptor kinase inhibitors
Manley, Paul W.,Furet, Pascal,Bold, Guido,Brüggen, Josef,Mestan, Jürgen,Meyer, Thomas,Schnell, Christian R.,Wood, Jeanette,Haberey, Martin,Huth, Andreas,Krüger, Martin,Menrad, Andreas,Ottow, Eckhard,Seidelmann, Dieter,Siemeister, Gerhard,Thierauch, Karl-Heinz
, p. 5687 - 5693 (2002)
Two readily synthesized anthranilamide, VEGF receptor tyrosine kinase inhibitors have been prepared and evaluated as angiogenesis inhibitors. 2-[(4-Pyridyl)methyl]amino-N-[3-(trifluoromethyl)phenyl]benzamide (5) and N-3-isoquinolinyl-2-[(4-pyridinylmethyl
Synthesis of novel piperazine-linked anthranilic acids as potential small molecule kinase inhibitors
Chakravorty, Santanu,Klein, Hanna F.,Hodson, Luke E.,Rabillier, Matthias,Fang, Zhizhou,Richters, Andre,Pelly, Stephen C.,Rauh, Daniel,Van Otterlo, Willem A.L.
, p. 71 - 79 (2014/06/09)
Substituted anthranilic acid and piperazines were used as building blocks to prepare two libraries of compounds, with the aim being that they would exhibit biochemical activity as small molecule kinase inhibitors. The synthesized anthranilamidepiperazine
