38558-72-4

Basic information

• Product Name: 2,5-Dihydroxy-3,6-bis(4-methoxyphenyl)-2,5-cyclohexadiene-1,4-dione
• Synonyms: 2,5-Dihydroxy-3,6-bis(4-methoxyphenyl)-2,5-cyclohexadiene-1,4-dione
• CAS NO: 38558-72-4
• Molecular Formula: C₂₀H₁₆O₆
• Molecular Weight: 0
• Mol File: 38558-72-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Dihydroxy-3,6-bis(4-methoxyphenyl)-2,5-cyclohexadiene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dihydroxy-3,6-bis(4-methoxyphenyl)-2,5-cyclohexadiene-1,4-dione(38558-72-4)
• EPA Substance Registry System: 2,5-Dihydroxy-3,6-bis(4-methoxyphenyl)-2,5-cyclohexadiene-1,4-dione(38558-72-4)

Safety Data

• Hazardous Substances Data: 38558-72-4(Hazardous Substances Data)

Usage

Molecular weight

322.36 g/mol

Chemical structure

A cyclohexadiene ring with two hydroxyl groups at positions 2 and 5, and two 4-methoxyphenyl groups at positions 3 and 6.

Natural occurrence

Found in the creosote bush.

Antioxidant properties

Nordihydroguaiaretic acid (NDGA) is a potent antioxidant.

Anti-inflammatory properties

NDGA exhibits anti-inflammatory properties.

Anti-cancer properties

NDGA has been studied for its potential use in treating cancer.

Anti-viral properties

NDGA exhibits anti-viral properties.

Potential use in treating diseases

NDGA has been studied for its potential use in treating various diseases, including cancer, diabetes, and viral infections.

Traditional medicine

NDGA has been used in traditional medicine for its wound healing and analgesic effects.

Modulation of cellular pathways

NDGA's ability to modulate multiple cellular pathways makes it a promising compound for further research and potential therapeutic development.

Upstream product

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• 64080-66-6 2,5-dichloro-3,6-di(p-methoxyphenyl)-1,4-benzoquinone 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 

Downstream Products

• 121254-68-0 4,7-Bis-(4-methoxyphenyl)-1,3-benzodioxol-2,5,6-trion 
• 121254-61-3 C₂₆H₂₂O₈ 
• 121254-60-2 C₂₆H₂₂O₈ 
• 121254-54-4 4,4''-Di-O-methylspiromentin A 

Relevant articles and documents

Discovery of a novel inhibitor of NAD(P)+-dependent malic enzyme (ME2) by high-throughput screening

Aim: Malic enzymes are oxidative decarboxylases with NAD+ or NAD(P)+ as cofactor that catalyze the conversion of L-malate to pyruvate and CO2. The aim of this study was to discover and characterize a potent inhibitor of hu