38560-24-6Relevant academic research and scientific papers
Arylamide as Potential Selective Inhibitor for Matrix Metalloproteinase 9 (MMP9): Design, Synthesis, Biological Evaluation, and Molecular Modeling
Al-Najjar, Belal,Dewa, Sangga P.,Hariono, Maywan,Jati, Benedictus W.,Jenie, Riris I.,Julianus, Jeffry,Nugroho, Ervan S.,Nuwarda, Rina F.,Putra, Kevin C.,Qodria, Lailatul,Ramadani, Ratna D.,Rollando, Rollando,Tiara, Reynaldo,Wahab, Habibah A.,Wisnumurti, Yohanes K.,Yusuf, Muhammad
, (2020/01/21)
Previous studies have reported that compounds bearing an arylamide linked to a heterocyclic planar ring have successfully inhibited the hemopexin-like domain (PEX9) of matrix metalloproteinase 9 (MMP9). PEX9 has been suggested to be more selectively targe
Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase
Huang, Ling,Luo, Zonghua,He, Feng,Lu, Jing,Li, Xingshu
experimental part, p. 4475 - 4484 (2010/08/22)
A series of novel berberine derivatives were designed, synthesized, and biologically evaluated as inhibitors of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Among these derivatives, compound 48a, berberine linked with 3-methylpyridi
Synthesis of some substituted pyrazinopyridoindoles and 3D QSAR studies along with related compounds: Piperazines, piperidines, pyrazinoisoquinolines, and diphenhydramine, and its semi-rigid analogs as antihistamines (H1)
Saxena, Mridula,Gaur, Stuti,Prathipati, Philip,Saxena, Anil K.
, p. 8249 - 8258 (2007/10/03)
3D QSAR studies on the title compounds led to the development of a model with three biophoric sites and six secondary sites viz. H-acceptor (ACC), H-donor (DON), heteroatom (presence), hydrophobic (hydrophobicity), steric (refractivity), and a ring (prese
A Convenient Synthesis of Monocyclic β-Lactams by Means of Solid-Liquid Phase Transfer Reactions
Takahata, Hiroki,Ohnishi, Yoshinori,Takehara, Hiroyuki,Tsuritani, Kazuko,Yamazaki, Takao
, p. 1063 - 1068 (2007/10/02)
The intramolecular N-alkylation of β-bromopropionamides (1) under phase transfer conditions afforded monocyclic N-substituted β-lactams (2) in high yields.In a similar manner, cyclization by N1-C4 bond formation gave 4-benzoyl-2-azet
