38568-41-1Relevant academic research and scientific papers
With the solid-state light-emitting nature of the rhodamine B derivative and its preparation and use
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Paragraph 0042; 0043; 0051; 0052; 0053; 0062; 0063, (2018/01/11)
The invention relates to rhodamine B derivatives with efficient solid luminescence properties, and preparation and application thereof. The compounds are prepared by modifying rhodamine B with an aggregation-induced luminescence or crystallization-induced luminescence unit. The preparation method comprises the following steps: carrying out ethanol esterification on 3-bromobenzene anhydride to obtain diesters, modifying the diesters by using an aggregation-induced luminescence or crystallization-induced luminescence unit, deprotecting the diesters, hydrolyzing to obtain dicarboxylic acids, and reacting the dicarboxylic acids with m-hydroxydiethylaniline to obtain the rhodamine B derivatives. The method enhances the purposiveness and directivity of the reaction synthesis, reduces the reaction step number and byproducts, and is simple for purification. The prepared rhodamine B derivatives can be used as a fluorescence sensor, biological staining agent, and cell dyeing imaging and organic semiconductor material.
LUMINESCENT TRIAZACYCLONONANE-BASED LANTHANIDE CHELATE COMPLEXES AS LABELLING REAGENTS
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Page/Page column 19, (2014/10/03)
The invention relates to a detectable molecule comprising a biospecific binding reactant attached to a macrocyclic luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of the formula (I) wherein, R1 consists of a li
Polymeric phthalates: Potential nonmigratory macromolecular plasticizers
Braslau, Rebecca,Schaeffner, Friederike,Earla, Aruna
, p. 1175 - 1184 (2013/03/29)
The synthesis of 4-vinyl-1,2-phthalate esters via Suzuki coupling is described, followed by nitroxide-mediated polymerization to prepare short homopolymers (degree of polymerization [DP] = 10-40, polydispersity index [PDI] = 1.1-1.3). Random copolymers with n-butyl acrylate (NBA) were prepared. Copolymers rich in phthalate ester residues of medium lengths (DP = 16-48, PDI = 1.2-1.8) and of shorter lengths (DP = 8-17, PDI = 1.2-1.3) were prepared. Copolymers rich in NBA residues were also prepared (DP = 13-19, PDI = 1.2-1.3). All polymers were oily liquids, with glass transitions temperatures undetected between 75 and -40 °C, indicating these polymeric phthalates hold promise as potential nonmigratory phthalate plasticizers. 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013. Copyright
METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF
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, (2013/02/27)
Compounds that modulate GluR5 activity and methods of using the same are disclosed.
Metallo-β-lactamase inhibitory activity of phthalic acid derivatives
Hiraiwa, Yukiko,Morinaka, Akihiro,Fukushima, Takayoshi,Kudo, Toshiaki
scheme or table, p. 5162 - 5165 (2010/03/24)
4-Butyl-3-methylphthalic acid was recognized as a metallo-β-lactamase inhibitor. The structure-activity relationship study of substituted phthalic acids afforded 3-phenylphthalic acid derivatives as potent IMP-1 inhibitors. On the other hand, 3-substituted with 4-hydroxyphenyl phthalic acid derivative displayed a potent combination effect with biapenem (BIPM) against Pseudomonas aeruginosa that produce IMP-1.
Novel thiophene derivatives, their process of preparation and the pharmaceutical compositions which comprise them
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Page/Page column 18, (2010/11/30)
A compound of formula (I) selected from: wherein: X represents oxygen or sulphur, Y represents oxygen, —NH— or —N(C1-C6)alkyl-, Ra represents hydrogen, halogen, (C1-C3)alkyl, hydroxyl or (C1-C3)alkoxy, Rb represents hydrogen, halogen or (C1-C3)alkyl, A represents phenyl, pyridyl, (C5-C6)cycloalkyl or (C5-C6)cycloalkenyl, R1 and R2 each represent a group selected from hydrogen, halogen, cyano, nitro, haloalkyl, haloalkoxy, alkyl, alkenyl, alkynyl, —OR4, —NR4R5, —S(O)nR4, —C(O)R4, —CO2R4, —O—C(O)R4, —C(O)NR4R5, —NR5—C(O)R4, —NR5—SO2R4, -T-CN, -T-OR4, -T-OCF3, -T- NR4R5, -T-S(O)nR4, -T-C(O)R4, -T-CO2R4, -T-O—C(O)R4, -T-C(O)NR4R5, -T-NR4—C(O)R5, -T-NR4—SO2R5, —R6 and -T-R6 in which n, T, R4, R5 and R6 are as defined in the description, R3 represents an —R7 or —U—R11 group in which R7 represents hydrogen, alkyl, aryl, cycloalkyl or heterocycle, U represents a linear or branched alkylene chain and R11 is defined in the description, their optical isomers or their addition salts with a pharmaceutically acceptable acid or base, and their use as inhibitor of metalloproteinase and more specifically of metalloproteinase-12.
Design, Synthesis and Cytotoxicity of 2-Hydroxy-1(H)-isoindole-1,3-dione (HISD) Derivatives Against CEM/O Human Leukemia Cells in vitro
Nandy, Partha,Avramis, Vassilios I.,Lien, Eric J.
, p. 664 - 679 (2007/10/03)
2-Hydroxy-1(H)-isoindole-1,3-dione derivatives (HISDs) possess a hydroxamic acid moiety which is built into an isoindoledione ring. Seven new compounds have been synthesized and tested for cytotoxicity against CEM human leukemia cell lines. Three active c
