38568-41-1

Basic information

• Product Name: 1,2-BENZENEDICARBOXYLIC ACID,4-BROMO-,1,2-DIETHYL ESTER
• Synonyms: 1,2-BENZENEDICARBOXYLIC ACID,4-BROMO-,1,2-DIETHYL ESTER;Diethyl 4-bromophthalate
• CAS NO: 38568-41-1
• Molecular Formula: C₁₂H₁₃BrO₄
• Molecular Weight: 301.1332
• Mol File: 38568-41-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 335.8°Cat760mmHg
• Flash Point: 156.9°C
• Appearance: /
• Density: 1.404g/cm³
• Vapor Pressure: 0.000117mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 1,2-BENZENEDICARBOXYLIC ACID,4-BROMO-,1,2-DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-BENZENEDICARBOXYLIC ACID,4-BROMO-,1,2-DIETHYL ESTER(38568-41-1)
• EPA Substance Registry System: 1,2-BENZENEDICARBOXYLIC ACID,4-BROMO-,1,2-DIETHYL ESTER(38568-41-1)

Safety Data

• Hazardous Substances Data: 38568-41-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H13BrO4/c1-3-16-11(14)9-6-5-8(13)7-10(9)12(15)17-4-2/h5-7H,3-4H2,1-2H3

Upstream product

• 22572-84-5 diethyl 4-aminophthalate 
• 86-90-8 4-bromophthalic anhydride 
• 64-17-5 ethanol 
• 106701-82-0 4-bromophthalic acid monosodium salt 
• 85-44-9 phthalic anhydride 
• 2050-19-3 4-nitrophthalic acid diethyl ester 
• 610-27-5 4-nitrophthalic acid 
• 84-66-2 Diethyl phthalate 
• 6968-28-1 4-bromophthalic acid 

Downstream Products

• 105903-40-0 4-cyano-phthalic acid diethyl ester 
• 34206-09-2 diethyl 4-vinylphthalate 
• 64169-34-2 5-bromophthalide 
• 943749-63-1 4-bromo-2-(carboxymethyl)benzoic acid 
• 260561-82-8 4-(8-Methoxy-1,4-benzodioxan-5-yl)phthalic acid 
• 6968-28-1 4-bromophthalic acid 

Relevant articles and documents

With the solid-state light-emitting nature of the rhodamine B derivative and its preparation and use

The invention relates to rhodamine B derivatives with efficient solid luminescence properties, and preparation and application thereof. The compounds are prepared by modifying rhodamine B with an aggregation-induced luminescence or crystallization-induced luminescence unit. The preparation method comprises the following steps: carrying out ethanol esterification on 3-bromobenzene anhydride to obtain diesters, modifying the diesters by using an aggregation-induced luminescence or crystallization-induced luminescence unit, deprotecting the diesters, hydrolyzing to obtain dicarboxylic acids, and reacting the dicarboxylic acids with m-hydroxydiethylaniline to obtain the rhodamine B derivatives. The method enhances the purposiveness and directivity of the reaction synthesis, reduces the reaction step number and byproducts, and is simple for purification. The prepared rhodamine B derivatives can be used as a fluorescence sensor, biological staining agent, and cell dyeing imaging and organic semiconductor material.

Polymeric phthalates: Potential nonmigratory macromolecular plasticizers

The synthesis of 4-vinyl-1,2-phthalate esters via Suzuki coupling is described, followed by nitroxide-mediated polymerization to prepare short homopolymers (degree of polymerization [DP] = 10-40, polydispersity index [PDI] = 1.1-1.3). Random copolymers with n-butyl acrylate (NBA) were prepared. Copolymers rich in phthalate ester residues of medium lengths (DP = 16-48, PDI = 1.2-1.8) and of shorter lengths (DP = 8-17, PDI = 1.2-1.3) were prepared. Copolymers rich in NBA residues were also prepared (DP = 13-19, PDI = 1.2-1.3). All polymers were oily liquids, with glass transitions temperatures undetected between 75 and -40 °C, indicating these polymeric phthalates hold promise as potential nonmigratory phthalate plasticizers. 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013. Copyright

Metallo-β-lactamase inhibitory activity of phthalic acid derivatives

4-Butyl-3-methylphthalic acid was recognized as a metallo-β-lactamase inhibitor. The structure-activity relationship study of substituted phthalic acids afforded 3-phenylphthalic acid derivatives as potent IMP-1 inhibitors. On the other hand, 3-substituted with 4-hydroxyphenyl phthalic acid derivative displayed a potent combination effect with biapenem (BIPM) against Pseudomonas aeruginosa that produce IMP-1.