385802-40-4Relevant articles and documents
Direct substitution of arylalkynyl carbinols provides access to diverse terminal acetylene building blocks
G-Dayanandan, Narendran,Scocchera, Eric W.,Keshipeddy, Santosh,Jones, Heather F.,Anderson, Amy C.,Wright, Dennis L.
supporting information, p. 142 - 145 (2017/11/27)
To develop next generation antifolates for the treatment of trimethoprim-resistant bacteria, synthetic methods were needed to prepare a diverse array of 3-aryl-propynes with various substitutions at the propargyl position. A direct route was sought whereb
SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION
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Page/Page column 317, (2008/12/05)
The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.
PROCESSES FOR THE PREPARATION OF COMPOUNDS
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Page/Page column 307, (2010/11/28)
The present invention provides improved synthetic methods for the preparation of compounds that modulate proliferation or differentiation in a cell or tissue.