38585-75-0

Basic information

• Product Name: Ethanamine, 2-[(2-pyridinylmethyl)thio]-
• CAS NO: 38585-75-0
• Molecular Formula: C8H12N2S
• Molecular Weight: 168.263
• Mol File: 38585-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanamine, 2-[(2-pyridinylmethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanamine, 2-[(2-pyridinylmethyl)thio]-(38585-75-0)
• EPA Substance Registry System: Ethanamine, 2-[(2-pyridinylmethyl)thio]-(38585-75-0)

Safety Data

• Hazardous Substances Data: 38585-75-0(Hazardous Substances Data)

Upstream product

• 4377-33-7 2-chloromethylpyridine 
• 156-57-0 2-mercaptoethylamine hydrochloride 

Downstream Products

• 116707-86-9 N''-cyano-N-phenyl-N'-<2-<2-pyridylmethylthio>ethyl>guanidine 
• 144284-39-9 N-[(E)-3-(1H-Imidazol-4-yl)-allyl]-N'-[2-(pyridin-2-ylmethylsulfanyl)-ethyl]-guanidine; compound with picric acid 
• 144153-34-4 N-Benzoyl-N'-[2-methyl-3-(5-methyl-1H-imidazol-4-yl)-propyl]-N''-[2-(pyridin-2-ylmethylsulfanyl)-ethyl]-guanidine 
• 144153-32-2 N-Benzoyl-N'-[3-(5-methyl-1H-imidazol-4-yl)-propyl]-N''-[2-(pyridin-2-ylmethylsulfanyl)-ethyl]-guanidine 
• 115414-20-5 N-<3-(imidazol-4-yl)propyl>-N'-<2-(2-pyridylmethylthio)ethyl>guanidine tripricrate 
• 144153-37-7 N-Benzoyl-N'-[2-(pyridin-2-ylmethylsulfanyl)-ethyl]-N''-[(E)-3-(1-trityl-1H-imidazol-4-yl)-allyl]-guanidine 
• 106669-33-4 N-Benzoyl-N'-[3-(1H-imidazol-4-yl)-propyl]-N''-[2-(pyridin-2-ylmethylsulfanyl)-ethyl]-guanidine 
• 116707-83-6 N-phenyl-N'-<2-<2-pyridylmethylthio>ethyl>thiourea 
• 116707-80-3 N-phenyl-N'-<2-<2-pyridylmethylthio>ethyl>urea 

Relevant articles and documents

Homo- and Heterodinuclear Rh and Ir Complexes Supported by SNnMixed-Donor Ligands (n = 2–4): Stereochemistry and Coordination-Site-Exchange Reactions of Cp*M (M = Rh, Ir) Units

A series of SNnmixed-donor ligands [n = 2: H2NC2H4SCH2-2-pyridyl (2-NSpy) (1a), H2NC2H4SCH2-4-pyridyl (4-NSpy) (1b), n = 3: 2-pyridylCH2NHC2H4SCH2-2-pyridyl (2-pyNSpy) (2), n = 4: (2-pyridylCH2)2NC2H4SCH2-2-pyridyl (2-py2NSpy) (3)] was utilized to support homo- and heterodinuclear complexes including Cp*MIIIunits (M = Rh, Ir; Cp* = pentamethylcyclopentadienyl). Reactions of [Cp*MCl2]2with 2-pyNSpy (2), 2-py2NSpy (3), and 4-NSpy (1b) afforded homodinulear complexes, [(Cp*MCl)(2-pyNSpy)(Cp*MCl)](PF6)2[M = Rh (5a), Ir (5b)], [(Cp*M)(2-py2NSpy)(Cp*MCl)](PF6)3[M = Rh (6a), Ir (6b)], [(Cp*MCl)(4-NSpy)(Cp*MCl2)]Cl [M = Rh (8a), Ir (8b)]. Heterodinuclear complexes [(Cp*MCl)(4-NSpy)(Cp*M′Cl2)]Cl [M, M′ = Rh, Ir (8c), Ir, Rh (8d)] were prepared using mononuclear complexes [(Cp*MCl)(4-NSpy)]Cl [M = Rh (7a), Ir (7b)] reacted with [Cp*MCl2]2(M = Ir, Rh), respectively. Complexes 5–8 were characterized by X-ray crystallography to determine the configurations around the M, M′, S, and N centers. The solid-state structures of 6 are retained in acetonitrile solution whereas four diastereomers are generated in the case of 5 due to low stereoselectivity around the coordinated amine nitrogen atom, in contrast to the sulfur atom. Heterodinuclear complexes 8c,d are unstable in solution at 55 °C, readily affording mixtures of 8a–d via intra- and intermolecular coordination-site-exchange reactions of Cp*M fragments between the SN moiety and the py site. In order to evaluate the selectivity of Cp*M fragments for the SN and py coordination sites, several competitive reactions of [Cp*MCl2]2(M = Rh, Ir) with H2NC2H4SCH2C6H5(NSph) (4) and/or 4-methylpyridine (4-Mepy) were carried out to demonstrate predominant formation of iridium complexes 9b and 10b among [(Cp*MCl)(NSph)]Cl [M = Rh (9a), Ir (9b)] and [(Cp*MCl)(4-Mepy)]Cl [M = Rh (10a), Ir (10b)]. These reactions indicated higher affinity of the Cp*Ir fragment to both the NS and py sites relative to the rhodium analogue.