3859-39-0Relevant academic research and scientific papers
A new and efficient route for 1,3,3′-triketones
Lim, Sunkwon,Min, Yosep,Choi, Bohyun,Kim, Daesig,Yoon, Il,Lee, Shim Sung,Lee, Ik-Mo
, p. 7645 - 7649 (2001)
Cyclic and acyclic 1,3,3′-triketones were prepared by the reactions adopting β-diketones and anhydrides in the presence of barium or strontium hydrides in high yields. Crystal structure of 4-acetyl-2,2,6,6-tetramethyl-3,5-heptanedione (3a) represented the
Activator-free reactions of carboxylic ortho esters with cyclic β-diketones
Balaneva,Shestak,Novikov,Glazunov
, p. 1584 - 1598 (2021/09/08)
The reaction mechanisms of cyclic 1,3-diketones with trialkyl orthoformates and trimethyl orthoacetate in the absence of activators were theoretically and experimentally studied. The reactions proceed via C-C-coupling of the ionized forms of the reactants giving dialkyl acetals, which further transform into vinyl ethers. The reactions of the latter with ortho esters afford aldehydes (ketones). Related 2-acetylcyclopentanone reacts with trimethyl orthoacetate under argon to form a mixture of methyl enol ethers, whereas in the presence of air oxygen dimethyl glutarate is formed.
SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF
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Page/Page column 224, (2018/04/27)
The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients.
Preparation of fluorine-containing exo- and endocyclic enamine derivatives of 2-acylcyclopentane-1,3-diones
Khlebnikova,Piven',Lakhvich
, p. 465 - 473 (2014/05/20)
The interaction of aromatic amines (4-fluorinebenzylamine, 3-trifluoromethylbenzylamine, 4-fluoroaniline, or 3,4-difluoroaniline) with either 2-acylcyclopentane-1,3-diones (fluorine-substituted or fluorine-free) or their enol derivatives (chlorovinyldiket
Platinum(II) cationic complexes with derivatives of 2-acyl-1,3- cyclopentanedions
Khlebnikova,Merkushin,Lakhvich
, p. 669 - 676 (2008/02/02)
Cis-Diammineplatinum(II) complexes containing 2-acyl-1,3-cyclopentadion fragments as a bidentate acido ligand were prepared by the transformation of cis-diamminediiodoplatinum(II) to cis-diamminesulfatoplatinum(II) under the action of silver sulfate with
SYNTHESIS AND SOME REACTIONS OF 2-ACYCLOPENTANE-1,3-DIONES
Lakhvich, F. A.,Khlebnikova, T. S.,Akhrem, A. A.
, p. 2280 - 2286 (2007/10/02)
2-Acylcyclopentane-1,3-diones were synthesized by O-C-isomerization of the enol esters of cyclopentane-1,3-dione by the action of aluminium chloride.The enol esters are formed during the O-acylation of cyclopentane-1,3-dione by carboxylic acid chlorides i
