386212-69-7

Basic information

• Product Name: (Z,Z)-8-[4-[3,6-Dioxo-5-[4-(thien-2-ylcarboxamido)benzylidene]piperazin-2-ylidenemethyl]phenoxy]octanoic acid
• Synonyms: XR-11211
• CAS NO: 386212-69-7
• Molecular Formula: C₃₁H₃₁N₃O₆S
• Molecular Weight: 573.67322
• Mol File: 386212-69-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z,Z)-8-[4-[3,6-Dioxo-5-[4-(thien-2-ylcarboxamido)benzylidene]piperazin-2-ylidenemethyl]phenoxy]octanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z,Z)-8-[4-[3,6-Dioxo-5-[4-(thien-2-ylcarboxamido)benzylidene]piperazin-2-ylidenemethyl]phenoxy]octanoic acid(386212-69-7)
• EPA Substance Registry System: (Z,Z)-8-[4-[3,6-Dioxo-5-[4-(thien-2-ylcarboxamido)benzylidene]piperazin-2-ylidenemethyl]phenoxy]octanoic acid(386212-69-7)

Safety Data

• Hazardous Substances Data: 386212-69-7(Hazardous Substances Data)

Upstream product

• 19073-14-4 4-(1,3-dioxolan-2-yl)aniline 
• 386212-62-0 methyl 8-(4-formylphenoxy)octanoate 
• 174766-74-6 4-(2-thiophenecarboxamido)benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 555-16-8 4-nitrobenzaldehdye 
• 2403-53-4 2-(4-nitrophenyl)-1,3-dioxolane 
• 26825-92-3 methyl 8-bromooctanoate 
• 386212-70-0 8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-amino]-phenyl}-meth-(Z)-ylidene]-piperazin-(2Z)-ylidenemethyl]-phenoxy}-octanoic acid methyl ester 

Relevant articles and documents

Synthesis and in vitro evaluation of a series of diketopiperazine inhibitors of plasminogen activator inhibitor-1

We have synthesized and evaluated a series of diketopiperazine-based inhibitors of PAI-1. These studies resulted in the identification of 34 which inhibited PAI-1 in vitro with an IC50 = 0.2 μM. The synthesis and SAR of these compounds are desc