386235-52-5

Upstream product

• 119139-14-9 3-bromo-4-(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 386235-55-8 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-(3-methoxy-naphthalen-2-yl)-1-methyl-pyrrole-2,5-dione 
• 876017-26-4 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-(2-methoxyphenyl)-1-methylpyrrole-2,5-dione 
• 876017-32-2 2-methyl-8-(benzenesulfonyl)benzo[a]pyrrolo[3,4-c]carbazole-1,3(2H,8H)-dione 
• 876017-30-0 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-(2-bromophenyl)-1-methylpyrrole-2,5-dione 
• 386235-60-5 trifluoromethanesulfonic acid 3-[4-(1-benzenesulfonyl-1H-indol-3-yl)-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]naphthalen-2-yl ester 
• 386235-58-1 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-(3-hydroxy-naphthalen-2-yl)-1-methyl-pyrrole-2,5-dione 
• 876017-28-6 trifluoro-methanesulfonic acid 2-[4-(1-benzenesulfonyl-1H-indol-3-yl)-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-phenyl ester 
• 876017-27-5 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-(2-hydroxyphenyl)-1-methylpyrrole-2,5-dione 
• 876017-31-1 3-(2-bromophenyl)-4-(1H-indol-3-yl)-1-methylpyrrole-2,5-dione 

Relevant academic research and scientific papers

Synthesis of naphthopyrrolo[3,4-c]carbazoles

New naphthocarbazoles 1 were built from protected 3-(3-indolyl)-4-bromo-N-methylmaleimide in four steps using palladium-catalysed cross-coupling reactions such as Suzuki reaction of 3-methoxy-2-boronic acid and Heck cyclisation of triflate.

Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents

We report the efficient synthesis involving palladium-catalyzed reactions and biological evaluation of new naphthocarbazoles designed as potential anticancer agents. The use of 5- and 6-benzyloxyindoles generated three substitution sites which were succes