38627-51-9 Usage
Molecular Weight
265.34 g/mol
Structure
Carbazole derivative with an ethyl group at the 9-position and a carbonyl group at the 2-position
Class
Ketones
Appearance
Solid or crystalline
Solubility
Soluble in organic solvents like ethanol, acetone, and dichloromethane
Stability
Stable under normal conditions, sensitive to strong acids and bases
Synthesis
Obtained through various synthetic routes, such as Friedel-Crafts acylation or by reacting carbazole with ethyl propiolate
Applications
Building block for organic compounds
Used in pharmaceuticals, dyes, and materials
Potential use in organic electronics due to high thermal stability and electron transport properties
Studied for use as a photoredox catalyst in organic reactions
Safety
Handle with care, avoid contact with skin and eyes, use appropriate protective measures
Storage
Store in a cool, dry, and well-ventilated area, away from heat and open flames, in a tightly sealed container
Environmental Impact
Low to moderate toxicity, but proper disposal and handling are necessary to minimize environmental impact
Regulatory Status
May be subject to specific regulations depending on the region and intended use.
Check Digit Verification of cas no
The CAS Registry Mumber 38627-51-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,6,2 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 38627-51:
(7*3)+(6*8)+(5*6)+(4*2)+(3*7)+(2*5)+(1*1)=139
139 % 10 = 9
So 38627-51-9 is a valid CAS Registry Number.
38627-51-9Relevant academic research and scientific papers
Bismuth(III) Triflate Catalyzed Three-Component Reactions of Indoles, Ketones, and α-Bromoacetaldehyde Acetals Enable Indole-to-Carbazole Transformation
Gu, Yanlong,Huang, Wenbo,Chen, Shaomin,Wang, Xin
supporting information, p. 4285 - 4289 (2018/07/29)
A three-component reaction of indoles, α-bromoacetaldehyde acetals, and ketones was developed by using bismuth(III) triflate as the catalyst to realize a straightforward approach for synthesizing carbazole derivatives. The reaction was established mechanistically through the autotandem catalysis of Bi(OTf)3 in the following two steps: (i) Friedel-Crafts-type alkylation of indole with α-bromoacetaldehyde acetal, which produced a tryptaldehyde-type intermediate and (ii) [4 + 2] annulation of this intermediate with the ketone component.
