3865-15-4

Usage

Uses

Used in Pharmaceutical Industry:
Phenol, 3-amino-, 4-methylbenzenesulfonate (ester) is used as a reactant for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key intermediate in the production of specific drugs.
Phenol, 3-amino-, 4-methylbenzenesulfonate (ester) is used as a building block for the synthesis of 2-methyl-5-(2,3,4,5,6-pentafluorophenyl)benzothiazole, which is an important compound in the development of new pharmaceuticals with potential therapeutic applications.
Additionally, Phenol, 3-amino-, 4-methylbenzenesulfonate (ester) is used as a starting material for the synthesis of 4-[(2'',3'',4'',5'',6''-pentafluoro-1,1''-biphenyl-3-yl)amino]benzonitrile, a compound that may have applications in the development of new drugs targeting specific biological pathways.

Upstream product

• 3899-90-9 3-nitrophenyl 4-methylbenzenesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 591-27-5 m-Hydroxyaniline 

Downstream Products

• 134654-01-6 m-(2-imidazolylazo)phenol 
• 210907-84-9 3-aminophenylboronic acid pinacolate 
• 1515854-68-8 C₂₁H₂₉NO₉S₃ 
• 1326311-80-1 3-((4-(tert-butyl)phenyl)amino)benzonitrile 
• 2237-30-1 m-cyanoaniline 
• 232938-43-1 N-(p-toluenesulphonyl)-N'-(3-(p-toluenesulphonyloxyphenyl))urea 
• 121942-79-8 3-(N-methyl-3'-p-toluenesulfonyloxyanilino)cyclohex-2-en-1-one 
• 121984-76-7 Toluene-4-sulfonic acid 3-methylamino-phenyl ester 
• 121942-78-7 Toluene-4-sulfonic acid 3-ethoxycarbonylamino-phenyl ester 
• 134654-00-5 m-(2-imidazolylazo)phenyl p-toluenesulfonate 
• 89277-86-1 diisopropyl 3-aminophenylphosphonate 

Relevant academic research and scientific papers

m-(p-tolylsulfonyloxy)aniline

In the title compound, 3-aminophenyl 4-toluene-sulfonate, C13H13NO3S, the dihedral angle between the toluene and aniline moieties is 64.26(5)°. The crystal structure is stabilized by N-H...O intermolecular hydrogen bonds i

A heat-sensitive structure containing sulfonylurea preparation method of the developer (by machine translation)

The invention discloses a heat-sensitive structure containing sulfonylurea preparation method of the developer, comprising the following steps: (1) esterification: m-aminophenol and toluene sulfonyl chloride under alkaline condition to obtain 3 - amino ph

Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls. Copyright

Hydrogen Bonding Induced Solid State Supramolecular Assemblies of Selective O-Tosyl and N-Tosyl Derivatives of 3-Aminophenol

Self-organisation via hydrogen bonding in the supramolecular assembly of selective mono-tosyl derivative of 3-aminophenol having free amino group (1) and free hydroxyl group (2) respectively, has been demonstrated. Compound 1 is stablised in the solid state forming a sixteen-membered hydrogen bonded structure in the self-assembly and compound 2 forms a column like structure with alternate different grooves.

General Base Catalysis by Hydroxocopper(II) Ion and Existence of Addition Intermediate in Hydrolysis of m-(2-Imidazolylazo)phenyl p-Toluenesulfonate

Rates of the hydrolysis of m-(2-imidazolylazo)phenyl p-toluenesulfonate (1) were measured in the presence of Cu(II) ion.Saturation behavior was observed for the dependence on of the absorbance (Abs) of 1 or that of the pseudo-first-order rate con