38662-75-8Relevant academic research and scientific papers
Certain N,N'-disubstituted guanidine compounds and their use
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, (2008/06/13)
N-(4-Imidazolyl)propyl-N'-heterocyclomethylthioethyl guanidines which are selective histamine H2 -receptor agonists.
GUANIDINO, THIOUREIDO AND ISOTHIOUREIDO DERIVATIVES CONTAINING IMIDAZOLE GROUPS
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, (2008/06/13)
The compounds are C 2-C 8 straight chain alkanes terminally substituted, symmetrically or unsymmetrically, by N-(N'-substituted guanidino), N-(N',N"-disubstituted guanidino), N-(N'-substituted thioureido), N-(nitromethylene amidino) or S-(N-substituted isothioureido) groups. Two compounds of the invention are 1,3-bis-N'-(2-(5-methyl-4-imidazolylmethylthio)ethyl)guanidino!propane and 1,3-bis-S-(N-2-(5-methyl-4-imidazolylmethylthio)ethyl)isothioureido!propane. The compounds of this invention are inhibitors of H-2 histamine receptors. "
PHARMACOLOGICALLY ACTIVE THIOUREA AND UREA COMPOUNDS
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, (2008/06/13)
The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
