386748-53-4

Upstream product

• 936-72-1 allyl o-tolyl ether 
• 95-48-7 ortho-cresol 
• 386748-51-2 (+)-(1S,5S)-5-isopropenyl-3-[2-(2-methoxy-3-methylphenyl)ethyl]-2,4,4-trimethylcyclohex-2-enol 
• 386748-50-1 (+)-(5S)-5-isopropenyl-3-[2-(2-methoxy-3-methylphenyl)ethyl]-2,4,4-trimethylcyclohex-2-enone 
• 386748-49-8 2-(2-methoxy-3-methylphenyl)ethanol 
• 386748-48-7 2-(2-bromoethyl)-6-methylanisole 
• 53948-45-1 1-allyl-2-methoxy-3-methylbenzene 
• 3354-58-3 2-allyl-6-methylphenol 
• 386748-52-3 (+)-(1S,5S)-5-isopropenyl-3-[2-(2-methoxy-3-methylphenyl)ethyl]-2,4,4-trimethylcyclohex-2-enyl methyl ether 

Relevant academic research and scientific papers

Enantiospecific synthesis of B-seco-C-aromatic taxanes

A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic taxanes starting from monoterpene (R)-carvone is described. Coupling of 6,6-dimethylcarvone 5 with appropriate arylethyl bromides followed by oxidation generates the enones 7, 15, 25, which are transformed into the 20-nor-B-seco-C-aromatic taxane derivatives 11, 17 and B-seco-C-aromatic taxane derivative 29 via degradation of the isopropenyl group.