38680-47-6

Upstream product

• 96728-44-8 4-<2'-(m-methoxyphenyl)ethyl>-7a-methyl-4a,2'-oxyindan-3,7-dione 
• 96728-34-6 cis-1-(m-methoxyphenyl)-2-<β-(2-methyl-1,3-dioxocyclopent-2-yl)propionyl>cyclopropane 
• 96728-33-5 trans-1-(m-methoxyphenyl)-2-<β-(2-methyl-1,3-dioxocyclopent-2-yl)propionyl>cyclopropane 
• 119087-33-1 3-Bromo-1-[2-(3-methoxy-phenyl)-cyclopropyl]-propan-1-one 
• 83177-88-2 3-methoxy-6ξ-chloro-9,10-secoestra-1,3,5(10),8(14)-tetraene-9,17-dione 
• 64-19-7 acetic acid 
• 38680-39-6 3-methoxy-6ξ-hydroxy-9,10-secoestra-1,3,5(10),8(14)-tetraene-9,17-dione 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

Total Synthesis of Aromatic Steroids

The coupling reaction of m-methoxystyrene (1) and 4-bromo-1-diazo-2-butanone (2) over Pd(OAc)2 gave trans and cis (ratio 7:1) cyclopropane derivatives 3a and 3b, which were used for the alkylation of 2-methylcyclopentane-1,3-dione to afford triketones 4a

7,7A-Dihydro-4-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-7a-alkyl-1, 5(6H)-indandiones,3,4,8,8a-tetrahydro-5-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-8a-alkyl-1,6(7H)-naphthalenediones and processes for the preparation thereof utilizing asymmetric induction

A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically