38689-20-2Relevant academic research and scientific papers
Synthesis and reactivity of benzoxa(thia)zol-2-thiones: New route to 2- alkylthiobenzoxa(thia)zoles
Harizi, Abdallah,Romdhane, Anis,Mighri, Zine
, p. 5833 - 5835 (2000)
The reaction of aromatic primary amines 1 with carbon disulfide in the presence of a catalytic amount of triethylamine followed by treatment with aqueous hydrogen peroxide leads to the corresponding benzoxa-(thia)zol-2- thiones 3a-c which can be transformed with iminoethers into 2- alkylthiobenzoxa(thia)zoles 5a-h in good yields (64-85%). (C) 2000 Elsevier Science Ltd.
Reaction of Benzoxazoline-2-thiones with Alkyl Halides
Yamato, Masatoshi,Takeuchi, Yasuo,Hashigaki, Kuniko,Hirota, Takashi
, p. 733 - 736 (2007/10/02)
The effect of the solvent on the reaction of benzoxazoline-2-thiones with alkyl halides was studied.The reaction of 1 with alkyl halides and potassium carbonate in dimethylformamide (DMF) gave the corresponding 2-alkylthiobenzoxazoles (2), but the same reaction gave 2-methoxybenzoxazoles (4a) when methanol was used in place of DMF as the solvent.On the other hand, the reaction of 1, methyl iodide, alcohol, and sodium hydride in tetrahydrofuran (THF) gave 2-phenols (5).
