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Usage

Uses

Used in Pharmaceutical Industry:
(2-hydroxy-4-methylphenyl)acetic acid is used as an active pharmaceutical ingredient for its potential therapeutic effects. Its antioxidant properties make it a candidate for the development of treatments targeting conditions associated with oxidative stress, such as neurodegenerative diseases and aging.
Used in Organic Synthesis:
As a precursor, (2-hydroxy-4-methylphenyl)acetic acid is used in the synthesis of various organic compounds and pharmaceuticals. Its versatility in chemical reactions allows for the creation of a wide range of products, contributing to the advancement of the chemical and pharmaceutical industries.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, (2-hydroxy-4-methylphenyl)acetic acid is used as an antimicrobial agent in various applications, such as in the development of new antibiotics or as a component in disinfectants and sanitizers to combat microbial growth.
Used in Nutraceutical Industry:
Given its presence in certain plants and fruits, (2-hydroxy-4-methylphenyl)acetic acid can be utilized in the nutraceutical industry as a dietary supplement or functional food ingredient, potentially offering health benefits related to its antioxidant and antimicrobial activities.
Overall, (2-hydroxy-4-methylphenyl)acetic acid's diverse applications across different industries highlight its potential as a valuable compound for various purposes, from pharmaceutical development to organic synthesis and beyond.

Upstream product

• 117571-37-6 <4-methyl-2-(phenylmethoxy)phenyl>acetic acid 
• 50-85-1 2-hydroxy-p-toluic acid 
• 117571-34-3 4-methyl-2-(phenylmethoxy)benzenemethanol 
• 117571-35-4 1-(bromomethyl)-4-methyl-2-(phenylmethoxy)benzene 
• 433712-96-0 2-benzyloxy-4-methyl-benzoylchloride 
• 117571-33-2 4-methyl-2-(phenylmethoxy)benzoic acid 
• 117571-36-5 <4-methyl-2-(phenylmethoxy)phenyl>acetonitrile 
• 95-87-4 2,5-Dimethylphenol 
• 195210-73-2 2-[2-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-phenyl]-N,N-diethyl-acetamide 
• 4385-37-9 6-methyl-2,3-dihydrobenzo[b]furan-2-one 

Downstream Products

• 117570-83-9 2-[2-(Carboxymethyl)-5-methylphenoxy]benzoic acid 

Relevant academic research and scientific papers

Synthesis and Absolute Configuration of Two Natural Phenolic Homobenzyl Esters

Two recently identified natural phenolic homobenzyl esters, isolated from Phragmipedium calurum (an orchid) and Eupatorium fortunei TURCZ (a perennial herb in the Asteraceae family), respectively, were synthesized in enantiopure forms. By comparison of the optical rotations for the synthetic and the natural samples, the absolute configurations for the natural products were reliably assigned. The synthesis also enables establishment of the absolute configuration of a closely related natural homobenzyl alcohol and provided for the first time complete physical and spectroscopic data for two other natural homobenzyl esters. Two recently isolated natural phenolic homobenzyl esters were synthesized in enantiopure forms. The absolute configurations for these natural products were thus reliably assigned. En route to the total synthesis of the first target, complete physical and spectroscopic data for two other related natural products were made available for the first time. Configuration assignment of a third natural product was also achieved.

Compounds having antitumor and antibacterial properties

The novel class of xanthenone-4-acetic acids represented by the general formula (I) STR1 where R1 represents up to two of the groups lower alkyl, halogen, CF3, CN, NO2, NH2, CH2 COOH, OR2,

Potential Antitumor Agents. 58. Synthesis and Structure-Activity Relationships of Substituted Xanthenone-4-acetic Acids Active against the Colon 38 Tumor in Vivo

In a search for compounds related to flavoneacetic acid with activity against solid tumors, a series of methyl- methoxy-, chloro, nitro-, and hydroxy-substituted xanthenone-4-acetic acids have been synthesized and evaluated against subcutaneously implanted colon adenocarcinoma 38 in vivo, using a short-term histology assay as a primary screening system.A major goal of this work was to identify compounds with similar profiles of activity to that of flavoneacetic acid but of higher potency.The level of activity of the compounds appeared to depend more on the nature of the substituent than its positioning, in the order Cl > Me, OMe > NO2, OH.However, the potency of the compounds was related much more to the position rather than the nature of the substitution, with 5-substituted compounds being clearly the most dose potent. 5-Methylxanthenone-4-acetic acid has a similar level of activity to that of flavoneacetic acid in the test systems employed but is more than 7-fold as does potent.