38706-98-8Relevant academic research and scientific papers
Enzymes in organic chemistry, Part 4: Enantioselective hydrolysis of 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates with lipases from Aspergillus niger and Rhizopus oryzae. A comparative study
Eidenhammer, Gerhard,Hammerschmidt, Friedrich
, p. 748 - 754 (1996)
Racemic 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates (+)-4 are prepared and tested for kinetic resolution by lipases AP 6 and FAP 15. Both enzymes proved to be useful in terms of broadness of application, reaction rate and enantiomer
Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-β-lactamases
Lassaux, Patricia,Hamel, Matthieu,Gulea, Mihaela,Delbrück, Heinrich,Mercuri, Paola Sandra,Horsfall, Louise,Dehareng, Dominique,Kupper, Micha?l,Frère, Jean-Marie,Hoffmann, Kurt,Galleni, Moreno,Bebrone, Carine
supporting information; experimental part, p. 4862 - 4876 (2010/10/18)
Although commercialized inhibitors of active site serine β-lactamases are currently used in coadministration with antibiotic therapy, no clinically useful inhibitors of metallo-β-lactamases (MBLs) have yet been discovered. In this paper, we investigated t
