Enzymes in organic chemistry, Part 4: Enantioselective hydrolysis of 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates with lipases from Aspergillus niger and Rhizopus oryzae. A comparative study

DOI: 10.1055/s-1996-4288

Source and publish data:

Synthesis p. 748 - 754 (1996)

Update date:2022-09-26

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Authors:

Eidenhammer, Gerhard

Hammerschmidt, Friedrich

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Article abstract of DOI:10.1055/s-1996-4288

Racemic 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates (+)-4 are prepared and tested for kinetic resolution by lipases AP 6 and FAP 15. Both enzymes proved to be useful in terms of broadness of application, reaction rate and enantiomer

Full text of DOI:10.1055/s-1996-4288

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