Enzymes in organic chemistry, Part 4: Enantioselective hydrolysis of 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates with lipases from Aspergillus niger and Rhizopus oryzae. A comparative study

Article abstract of DOI:10.1055/s-1996-4288

Racemic 1-acyloxy(aryl)methyl- and 1-acyloxy(heteroaryl)methylphosphonates (+)-4 are prepared and tested for kinetic resolution by lipases AP 6 and FAP 15. Both enzymes proved to be useful in terms of broadness of application, reaction rate and enantiomer