38767-74-7

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 111-50-2 Adipic acid dichloride 
• 1071-71-2 ethyl 6-chloro-6-oxohexanoate 
• 35444-44-1 methyl adipoyl chloride 
• 167159-65-1 ethyl 6-(3,4-dimethoxy-(E)-oxobenzene)hexanoate 
• 57641-18-6 methyl 6-(3,4-dimethoxyphenyl)-6-oxohexanoate 
• 2035-75-8 adipic anhydride 

Downstream Products

• 132858-52-7 6-(3,4-dihydroxy-phenyl)-hexanoic acid methyl ester 
• 95301-42-1 6-(3,4-dihydroxy-phenyl)-hexanoic acid 
• 167159-13-9 2-<6-(cyclohexylthio)-6-(3,4-dimethoxyphenyl)-1-oxohexyl>-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 167159-24-2 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6-(3,4-dimethoxy-phenyl)-6-p-tolylsulfanyl-octan-1-one 
• 234080-63-8 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6-(3,4-dimethoxy-phenyl)-6-pentylsulfanyl-hexan-1-one 
• 234080-62-7 2-[6-(3,4-Dimethoxyphenyl)-1-oxo-6-[(phenylmethyl)-thio]hexyl]-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 167159-17-3 2-[6-(3,4-dimethoxyphenyl)-6-[(1,1-dimethylethyl)thio]-1-oxohexyl]-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 167159-51-5 2-<6-(3,4-dimethoxyphenyl)-6-hydroxy-1-oxooctyl>-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 167159-67-3 2-<6-(3,4-dimethoxyphenyl)-6-hydroxy-1-oxohexyl>-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 167159-66-2 2-<6-(3,4-dimethoxyphenyl)-1,6-dioxohexyl>-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 
• 57640-97-8 6-(3,4-Dimethoxy-phenyl)-6-oxo-hexanoic acid [2-(3,4-dimethoxy-phenyl)-ethyl]-amide 
• 53012-90-1 6-(3,4-dimethoxy-phenyl)-hexanoic acid 

Relevant academic research and scientific papers

Novel multidrug resistance reversal agents

A series of 59 α-aryl-α-thioether-alkyl, -alkanenitrile, and - alkanecarboxylic acid methyl ester tetrahydroisoquinoline and isoindoline derivatives (15a-48) were synthesized and evaluated as multidrug resistance (MDR) reversal agents. The compounds were