38786-79-7

Usage

Uses

Used in Organic Synthesis:
TETRAHYDRO-2H-PYRAN-2-ETHANOL is used as a solvent and a reagent in organic synthesis for its ability to dissolve a wide range of organic compounds and facilitate various chemical reactions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, TETRAHYDRO-2H-PYRAN-2-ETHANOL is utilized in the production of various medications due to its compatibility with active pharmaceutical ingredients and its role in enhancing the synthesis process.
Used in Perfumery and Fragrance Industry:
TETRAHYDRO-2H-PYRAN-2-ETHANOL is employed as a solvent in the creation of perfumes and fragrances, where it helps to dissolve and stabilize aromatic compounds, contributing to the final product's scent profile and longevity.

InChI:InChI=1/C7H14O2/c8-5-4-7-3-1-2-6-9-7/h7-8H,1-6H2

Upstream product

• 22408-41-9 Tetrahydropyranyl vinyl ether 
• 38786-78-6 (+/-)-ethyl tetrahydro-2H-pyran-2-acetate 
• 1050494-60-4 2-[(E/Z)-2-methoxyethenyl]tetrahydro-2H-pyran 
• 86266-57-1 2-(tetrahydropyran-2-yl)acetaldehyde 
• 17739-45-6 2-(2-bromoethoxy)tetrahydropyran 
• 110-87-2 3,4-dihydro-2H-pyran 
• 96251-91-1 ethyl cis/trans-7-hydroxy-2-heptenoate 
• 181273-30-3 (E)-7-(Tetrahydro-pyran-2-yloxy)-hept-2-enoic acid ethyl ester 

Downstream Products

• 86266-57-1 2-(tetrahydropyran-2-yl)acetaldehyde 
• 1312019-05-8 1-(1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-2-yl)-ethanol 
• 1221413-88-2 C₁₄H₁₈O₃ 
• 1359975-08-8 C₂₃H₂₉N₅O₄ 
• 1312019-09-2 toluene-4-sulfonic acid 1-(1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-yl)-vinyl ester 
• 1312019-08-1 1-(1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-2(S)-yl)-ethanone 
• 1312019-07-0 1-(1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-2(R)-yl)-ethanone 
• 1312019-11-6 2-[1-(4-methanesulfonyl-phenyl)-2-(tetrahydro-pyran-2-yl)-vinyl]-1H-pyrrolo[2,3-b]pyridine 
• 1312019-10-5 1-benzenesulfonyl-2-[1-(4-methanesulfonyl-phenyl)-2-(tetrahydro-pyran-2-yl)-vinyl]-1H-pyrrolo[2,3-b]pyridine 
• 1312019-06-9 1-(1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-2-yl)-ethanone 
• 860010-76-0 1-tetrahydro-2H-2-pyranylmethyl allyl-2-benzyloxy acetate 

Relevant academic research and scientific papers

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase is being pursued with computational guidance. Extension of azine-containing inhibitors into the entrance channel between Lys103 and Glu138 has led to the discovery of potent and structurally novel derivatives including dimeric inhibitors in an NNRTI-linker-NNRTI motif.

AZAINDOLE GLUCOKINASE ACTIVATORS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.

PURINE DERIVATIVES AS IMMUNOMODULATORS

The present invention includes novel compounds useful in the treatment of various disorders in particular infectious diseases, cancer, and allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, and as vaccine adjuvants

A novel synthesis of the north west portion of Lasonolide A - An anticancer macrolide using Claisen rearrangement

A simplified analogue of Lasonolide A (C23-C35 side chain) was synthesized using Fujisawa's stereoselective variant of the Ireland Claisen ester rearrangement.

Triisobutylaluminum-Assisted Reductive Rearrangement of Alkyl 1-Alkenyl Acetals: An Easy Synthesis of β-Alkoxy Alcohols

Alkyl 1-alkenyl acetals react with Al-i-Bu3 to give very good yields of β-alkoxy alcohols through a reductive rearrangement.The reaction is totally regioselective, but no stereocontrol occurs.