387860-54-0

Basic information

• Product Name: Ethanone, 1-[4-hydroxy-3-[(trimethylsilyl)ethynyl]phenyl]-
• CAS NO: 387860-54-0
• Molecular Formula: C13H16O2Si
• Molecular Weight: 232.354
• Mol File: 387860-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-hydroxy-3-[(trimethylsilyl)ethynyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-hydroxy-3-[(trimethylsilyl)ethynyl]phenyl]-(387860-54-0)
• EPA Substance Registry System: Ethanone, 1-[4-hydroxy-3-[(trimethylsilyl)ethynyl]phenyl]-(387860-54-0)

Safety Data

• Hazardous Substances Data: 387860-54-0(Hazardous Substances Data)

Upstream product

• 62615-24-1 4'-hydroxy-3'-iodoacetophenone 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 370565-08-5 p-acetyl-o-ethynylphenol 
• 121045-41-8 1-(2-phenyl-5-benzofuranyl)ethanone 

Relevant articles and documents

A microwave-enhanced, solventless Mannich condensation of terminal alkynes and secondary amines with para-formaldehyde on cuprous iodide doped alumina

A microwave-enhanced, solventless Mannich condensation of terminal alkynes and secondary amines with para-formaldehyde on cuprous iodide doped alumina has been developed. β-Aminoalkynes are generated in good yields. The reaction can be extended to include a cyclization, which affords 2-substituted benzo[b]furans. The chemoselectivity of the reaction indicates that terminal alkynes are much more reactive than enolizable ketones under the reaction conditions.