387877-71-6

Basic information

• Product Name: 2H-Pyrazino[2,1-b]quinazoline-4-propanamide, 1,3,4,6-tetrahydro-3,6-dioxo-1-(phenylmethyl)-N-(triphenylmethyl)-, (1R,4S)-
• CAS NO: 387877-71-6
• Molecular Formula: C40H34N4O3
• Molecular Weight: 618.735
• Mol File: 387877-71-6.mol

Chemical Properties

• CAS DataBase Reference: 2H-Pyrazino[2,1-b]quinazoline-4-propanamide, 1,3,4,6-tetrahydro-3,6-dioxo-1-(phenylmethyl)-N-(triphenylmethyl)-, (1R,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrazino[2,1-b]quinazoline-4-propanamide, 1,3,4,6-tetrahydro-3,6-dioxo-1-(phenylmethyl)-N-(triphenylmethyl)-, (1R,4S)-(387877-71-6)
• EPA Substance Registry System: 2H-Pyrazino[2,1-b]quinazoline-4-propanamide, 1,3,4,6-tetrahydro-3,6-dioxo-1-(phenylmethyl)-N-(triphenylmethyl)-, (1R,4S)-(387877-71-6)

Safety Data

• Hazardous Substances Data: 387877-71-6(Hazardous Substances Data)

Upstream product

• 118-92-3 anthranilic acid 
• 103321-58-0 Fmoc-D-phenylalanine acid chloride 
• 103321-57-9 2S-flouren-9-ylmethoxycarbonylamino-3-phenylpropionyl chloride 

Downstream Products

• 252032-23-8 (1R,4S)-1,3,4,6-tetrahydro-3,6-dioxo-1-(phenylmethyl)-2H-pyrazino[2,1-b]quinazoline-4-propanamide 

Relevant articles and documents

Total solid phase syntheses of the quinazoline alkaloids: Verrucines A and B and anacine

The first total syntheses of verrucines A and B and anacine (revised structure) were accomplished on Sasrin resin. This work confirmed the structure of verrucine A and unambiguously showed verrucine B to be a derivative of D-phenylalanine and L-glutamine. The study also proved that anacine and its epimer are quinazoline alkaloids, not benzodiazepines as originally proposed. 1-Hydroxyverrucine B, derived from air oxidization of verrucine B, was also isolated and characterized.