387882-75-9

Basic information

• Product Name: C₁₁H₁₅BrN₂S
• CAS NO: 387882-75-9
• Molecular Weight: 287.223
• Mol File: 387882-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₅BrN₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₅BrN₂S(387882-75-9)
• EPA Substance Registry System: C₁₁H₁₅BrN₂S(387882-75-9)

Safety Data

• Hazardous Substances Data: 387882-75-9(Hazardous Substances Data)

Upstream product

• 13037-60-0 1-bromo-2-isothiocyanatobenzene 
• 109-89-7 diethylamine 

Downstream Products

• 24255-48-9 N,N-diethylbenzo[d]thiazol-2-amine 

Relevant articles and documents

An "on-water" exploration of CuO nanoparticle catalysed synthesis of 2-aminobenzothiazoles

An "on-water" one-pot process has been engineered for the preparation of 2-aminobenzothiazole from ortho-halo (-F, -Cl, -Br and -I) substituted unsymmetrical thioureas. For ortho -I and -Br substrates the reactions afford 2-aminobenzothiazoles under metal free condition promoted by base. However, the relatively inert ortho -Cl and -F substrates undergo intramolecular arylthiolation only in the presence of CuO nanoparticles yielding 2-aminobenzothiazoles. This methodology provides easy access to aminobenzothiazoles utilising even the ortho -Cl and -F substrates. The catalyst is recyclable several times without loss of substantial activity. Other remarkable features include the wide range of functional group tolerance, absence of chromatographic purification (for ortho -I and -Br substrates) and providing moderate to excellent yield of the products under mild conditions, thus rendering the methodology as a highly eco-friendly alternative to the existing methods.