38796-03-1Relevant academic research and scientific papers
Cobalt-Catalyzed (E)-β-Selective Hydrogermylation of Terminal Alkynes
Radzhabov, Maxim R.,Mankad, Neal P.
supporting information, p. 3221 - 3226 (2021/05/04)
A cobalt-catalyzed method for the hydrogermylation of alkynes is reported, providing a selective and accessible route to (E)-β-vinyl(trialkyl)germanes from terminal alkynes and HGeBu3. As shown in multiple examples, the developed method demonstrates a broad functional group tolerance an practical utility for late-stage hydrogermylation of natural products. The method is compatible with alkynes bearing both aryl and alkyl substituents, providing unrivaled selectivity for previously challenging 1° alkyl-substituted alkynes. Moreover, the catalyst used in this method, Co2(CO)8, is a cheap and commercially available reagent. Conducted mechanistic studies supported the syn-addition of Bu3GeH to an alkyne π-complex.
Transition metal-catalyzed dehydrogenative germylation of olefins with tri-n-butylgermane
Furukawa, Naoyuki,Kourogi, Noriko,Seki, Yoshio,Kakiuchi, Fumitoshi,Murai, Shinji
, p. 3764 - 3767 (2008/10/08)
The catalyzed reaction of an excess of styrene with n-Bu3GeH using several ruthenium and rhodium complexes gave the corresponding vinylgermanes (α-trin-butylgermylstyrene, (Z)-β-tri-n-butylgermylstyrene, and (E)-β-tri-n-butylgermylstyrene), whi
