388072-77-3

Basic information

• Product Name: Carbamic acid, [(1S)-3-chloro-1-[(3,5-difluorophenyl)methyl]-2-oxopropyl]-, 1,1-dimethylethyl ester
• CAS NO: 388072-77-3
• Molecular Formula: C15H18ClF2NO3
• Molecular Weight: 333.763
• Mol File: 388072-77-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-3-chloro-1-[(3,5-difluorophenyl)methyl]-2-oxopropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-3-chloro-1-[(3,5-difluorophenyl)methyl]-2-oxopropyl]-, 1,1-dimethylethyl ester(388072-77-3)
• EPA Substance Registry System: Carbamic acid, [(1S)-3-chloro-1-[(3,5-difluorophenyl)methyl]-2-oxopropyl]-, 1,1-dimethylethyl ester(388072-77-3)

Safety Data

• Hazardous Substances Data: 388072-77-3(Hazardous Substances Data)

Upstream product

• 473567-47-4 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(3,5-difluorophenyl)propanoate 
• 593-71-5 Chloroiodomethane 
• 1634-04-4 tert-butyl methyl ether 

Downstream Products

• 388072-80-8 [(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-3-chloro-propyl]carbamic acid t-butyl ester 

Relevant articles and documents

BETA-SECRETASE INHIBITING COMPOUNDS

Disclosed are compounds represented by Formula (I) as defined in the specification, or pharmaceutically acceptable salts or isomers thereof, and a pharmaceutical composition for inhibiting beta-secretase activity comprising a therapeutically effective amount of the same.

Methods of treatment of amyloidosis using bi-aryl aspartyl protease inhibitors

The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS

The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.