388072-80-8 Usage
Description
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is a carbamic acid ester with a tert-butyl group, featuring a chiral center at the 1st and 2nd positions with the S-stereochemistry. (1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester also contains a chlorine atom and a difluoro-benzyl functional group, making it a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. As a chiral compound, it has potential applications in asymmetric catalysis and chiral resolution processes. Its hydroxy and carbamic acid functionality may also contribute to biological activity, highlighting its importance in medicinal chemistry research. However, due to its potential reactivity and toxicological properties, caution should be exercised when handling and using this compound.
Uses
Used in Pharmaceutical Synthesis:
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific biological activities.
Used in Agrochemical Synthesis:
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is used as an intermediate in the synthesis of agrochemicals to help create effective compounds for agricultural applications.
Used in Asymmetric Catalysis:
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is used as a chiral compound in asymmetric catalysis to facilitate the production of enantiomerically pure compounds, which are essential in various chemical and pharmaceutical processes.
Used in Chiral Resolution Processes:
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is used in chiral resolution processes to separate enantiomers, which is crucial for obtaining the desired biological activity and avoiding potential side effects in pharmaceuticals.
Used in Medicinal Chemistry Research:
(1S,2S)-[3-Chloro-1-(3,5-difluoro-benzyl)-2-hydroxy-propyl]-carbamic acid tert-butyl ester is used in medicinal chemistry research for its potential biological activity and its role in the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 388072-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,8,0,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 388072-80:
(8*3)+(7*8)+(6*8)+(5*0)+(4*7)+(3*2)+(2*8)+(1*0)=178
178 % 10 = 8
So 388072-80-8 is a valid CAS Registry Number.
388072-80-8Relevant articles and documents
BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY
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Page/Page column 35-36, (2009/04/25)
Disclosed are compounds represented by Formula (I) as defined in the specification, or pharmaceutically acceptable salts or isomers thereof, and a pharmaceutical composition for inhibiting beta-secretase activity comprising a therapeutically effective amo
Methods of treatment of amyloidosis using bi-aryl aspartyl protease inhibitors
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Page/Page column 42-43, (2010/02/15)
The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.
METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS
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Page/Page column 291; 293-294, (2010/02/14)
The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.
