388078-34-0Relevant articles and documents
Utilization of renewable formic acid from lignocellulosic biomass for the selective hydrogenation and/or N-methylation
Zhou, Chao-Zheng,Zhao, Yu-Rou,Tan, Fang-Fang,Guo, Yan-Jun,Li, Yang
, p. 4724 - 4728 (2021/09/06)
Lignocellulosic biomass is one of the most abundant renewable sources in nature. Herein, we have developed the utilization of renewable formic acid from lignocellulosic biomass as a hydrogen source and a carbon source for the selective hydrogenation and further N-methylation of various quinolines and the derivatives, various indoles under mild conditions in high efficiencies. N-methylation of various anilines is also developed. Mechanistic studies indicate that the hydrogenation occurs via a transfer hydrogenation pathway.
Catalytic system for efficiently catalyzing indole silanization and proton transfer hydrogenation
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Paragraph 0049; 0050; 0064; 0065; 0066; 0067, (2017/09/01)
The invention discloses a catalytic system for efficiently catalyzing indole silanization and proton transfer hydrogenation, and belongs to the technical field of organic synthesis. According to the catalytic system, indole and silane serve as raw materials, tris(pentafluorophenyl) boron (B (C6F5)3) serves as a catalyst, reaction is performed for 10 minutes at the indoor temperature to simultaneously achieve 3-position selective indole silanization and proton transfer hydrogenation or reaction is performed for 10-1440 minutes at the temperature ranging from 100 DEG C to 140 DEG C to achieve 3-position efficient and specific catalytic indole silanization. The catalytic system has the advantages that the catalytic system is convenient to operate, mild in reaction condition, rapid in reaction, high in conversion rate, less in catalyst consumption and applicable to various solvent systems or body systems without any solvents, raw materials are easily acquired, precious metal is omitted, a catalytic intermediate is high in stability and the like.
4-Fluoroanilines: Synthesis and decomposition
Zakrzewska,Kolehmainen,Osmialowski,Gawinecki
, p. 1 - 10 (2007/10/03)
Fourteen N- and/or 2-substituted 4-fluoroanilines were prepared (the series includes N-C2-bridged compounds). Some of them were found to be thermally unstable when dissolved in chloroform. Both 19F NMR spectra and comparison of GIAO-DFT calculated and experimental 13C chemical shifts were used to suggest decomposition products of 4-fluoroanilines.