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2,2-Dimethyl-1,3-cyclopentanedione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

3883-58-7

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3883-58-7 Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 1362, 1983 DOI: 10.1021/jo00156a046

Check Digit Verification of cas no

The CAS Registry Mumber 3883-58-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,8 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3883-58:
(6*3)+(5*8)+(4*8)+(3*3)+(2*5)+(1*8)=117
117 % 10 = 7
So 3883-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H10O2/c1-7(2)5(8)3-4-6(7)9/h3-4H2,1-2H3

3883-58-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-dimethylcyclopentane-1,3-dione

1.2 Other means of identification

Product number -
Other names 1,3-Cyclopentanedione,2,2-dimethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3883-58-7 SDS

3883-58-7Relevant academic research and scientific papers

Synthesis of 2,2-dimethyl-4-cyclopentene-1,3-dione and 5,5-dimethyl-4-hydroxy-2-cyclopenten-1-one

Kreiser, Wolfgang,Wiggermann, Annette,Krief, Alain,Swinnen, Dominique

, p. 7119 - 7122 (1996)

Enedione 1 and related rac- and optically active enones 2 bearing a hydroxyl- 2a or a protected- 2b-c or an activated - 2d 4-hydroxyl group at C-4 have been efficiently synthesized from cheap and readily available starting materials.

SYNTHESIS OF 2,2-DISUBSTITUTED 4,9-DIHYDROXY-1H-BENZ(f)INDENE-1,3(2H)DIONES. A MODEL SEQUENCE FOR THE SYNTHESIS OF FREDERICAMYCIN

Parker, Kathlyn A.,Koziski, Kathleen A.,Breault, Gloria

, p. 2181 - 2182 (1985)

Benzindenedione 3 was prepared as a model for fredericamycin.

Stereoselective synthesis of two potential metabolites of cis-metconazole

Budny, Marcin,W?odarczyk, Joanna,Muzio?, Tadeusz,Bosiak, Mariusz Jan,Wolan, Andrzej

, p. 4285 - 4288 (2017)

The stereoselective synthesis of compounds 5 and 6, potential hydroxylated metabolites of the agricultural fungicide cis-metconazole, is reported. In a key step of the initially surveyed synthetic route, hydrodechlorination of 12 was competitive with hydr

Selective Derivatization of N-Terminal Cysteines Using Cyclopentenediones

Brun, Omar,Agramunt, Jordi,Raich, Lluis,Rovira, Carme,Pedroso, Enrique,Grandas, Anna

, p. 4836 - 4839 (2016)

The outcome of the Michael-type reaction between thiols and 2,2-disubstituted cyclopentenediones varies depending on the thiol. Stable compounds with two fused rings were formed upon reaction with 1,2-aminothiols (such as N-terminal cysteines in peptides). Other thiols gave reversibly Michael-type adducts that were in equilibrium with the starting materials. This differential reactivity allows differently placed cysteines to be distinguished and has been exploited to prepare bioconjugates incorporating two or three different moieties.

A short, protecting group-free total synthesis of bruceollines D, E, and J

Lopchuk, Justin M.,Green, Ilene L.,Badenock, Jeanese C.,Gribble, Gordon W.

, p. 4485 - 4487 (2013)

A short, protecting group-free total synthesis of bruceollines D, E, and J has been achieved. The enantioselective reduction of bruceolline E with β-chlorodiisopinocampheylborane delivers both the natural and unnatural enantiomers of bruceolline J in excellent yields and enantioselectivities. Reduction with baker's yeast and sucrose was shown to provide the unnatural enantiomer of bruceolline J in 98% ee.

Methods of treating soft tissue defects

-

Page/Page column 62, (2016/06/01)

The specification discloses compositions and methods for treating a soft tissue defect of an individual.

Regio- and Stereoselective Syntheses of 7-Oxabicyclo[2.2.1]heptanes via a Gold(I)-Catalyzed Cycloisomerization of Alkynediols: Asymmetric Total Synthesis of Farnesiferol C

Gu, Yue-Qing,Zhang, Peng-Peng,Fu, Jun-Kai,Liu, Song,Lan, Yu,Gong, Jian-Xian,Yang, Zhen

supporting information, p. 1392 - 1397 (2016/05/19)

A highly regio- and stereoselective method to construct a broad range of 7-oxabicyclo[2.2.1]heptanes, which proceeds through a sequential reaction involving gold(I)-catalyzed cycloisomerization of alkynediols and sequential semi-pinacol-type 1,2-alkyl migration, was developed. The developed chemistry was applied to the asymmetric total synthesis of the natural product farnesiferol C.

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Duan, James J.-W.,Lu, Zhonghui,Jiang, Bin,Yang, Bingwei V.,Doweyko, Lidia M.,Nirschl, David S.,Haque, Lauren E.,Lin, Shuqun,Brown, Gregory,Hynes, John,Tokarski, John S.,Sack, John S.,Khan, Javed,Lippy, Jonathan S.,Zhang, Rosemary F.,Pitt, Sidney,Shen, Guoxiang,Pitts, William J.,Carter, Percy H.,Barrish, Joel C.,Nadler, Steven G.,Salter-Cid, Luisa M.,McKinnon, Murray,Fura, Aberra,Schieven, Gary L.,Wrobleski, Stephen T.

, p. 5721 - 5726 (2015/01/08)

A new class of Janus kinase (JAK) inhibitors was discovered using a rationally designed pyrrolo[1,2-b]pyridazine-3-carboxamide scaffold. Preliminary studies identified (R)-(2,2-dimethylcyclopentyl)amine as a preferred C4 substituent on the pyrrolopyridazi

PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

-

Page/Page column 107; 108, (2012/10/07)

Disclosed are compounds of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

Treatment of inflammatory bowel disease

-

, (2008/06/13)

Disclosed herein is a method comprising administering a compound to a mammal suffering from an inflammatory bowel disease for the treatment of said disease, said compound having a structure according to Formula I wherein X, Y, B, R2, R3, R4, R5, R6 and n have the meanings found herein.

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